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Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 132
  • TRIAL 
    Gtf2h5 antibody - N-terminal region (ARP55987_P050) in Mouse Heart using Western Blot

    Gtf2h5 antibody - N-terminal region (ARP55987_P050)

    Protein Name:General transcription factor IIH subunit 5
    Catalog #:ARP55987_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Gabpa Antibody - N-terminal region (ARP31186_P050) in Mouse Lung using Western Blot
    Gabpa Antibody - N-terminal region (ARP31186_P050) in Human heart using Western Blot
    Gabpa Antibody - N-terminal region (ARP31186_P050) in Human liver using Western Blot

    Gabpa Antibody - N-terminal region (ARP31186_P050)

    Protein Name:GA-binding protein alpha chain
    Catalog #:ARP31186_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Gatad2b antibody - C-terminal region (ARP39430_P050) in Mouse Brain using Western Blot

    Gatad2b antibody - C-terminal region (ARP39430_P050)

    Protein Name:Transcriptional repressor p66-beta
    Catalog #:ARP39430_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    GH1 antibody - C-terminal region (ARP41763_P050) in Human THP-1 using Western Blot

    GH1 antibody - C-terminal region (ARP41763_P050)

    Protein Name:Growth hormone 1 Ensembl ENSP00000343791
    Catalog #:ARP41763_P050
    Type: pAb
    Reacts with: Cow, Goat, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    GPRC6A antibody - C-terminal region (ARP64456_P050) in Human Jurkat using Western Blot

    GPRC6A antibody - C-terminal region (ARP64456_P050)

    Protein Name:G-protein coupled receptor family C group 6 member A
    Catalog #:ARP64456_P050
    Type: pAb
    Reacts with: Dog, Horse, Human, Yeast
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    GREB1 Antibody - N-terminal region (ARP34734_P050) in Human Pancreas Tumor using Western Blot

    GREB1 Antibody - N-terminal region (ARP34734_P050)

    Protein Name:Protein GREB1
    Catalog #:ARP34734_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Glra3 antibody - middle region (ARP35063_P050) in Mouse Small Intestine using Western Blot

    Glra3 antibody - middle region (ARP35063_P050)

    Protein Name:Glycine receptor subunit alpha-3
    Catalog #:ARP35063_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Gtf3c3 antibody - C-terminal region (ARP38950_P050) in Rat Liver using Western Blot

    Gtf3c3 antibody - C-terminal region (ARP38950_P050)

    Protein Name:General transcription factor IIIC, polypeptide 3, 102kDa (Predicted) EMBL EDL99063.1
    Catalog #:ARP38950_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    GDAP1 antibody - C-terminal region (ARP63896_P050) in Human OVCAR-3 using Western Blot

    GDAP1 antibody - C-terminal region (ARP63896_P050)

    Protein Name:Ganglioside-induced differentiation-associated protein 1
    Catalog #:ARP63896_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Gapdh Antibody - C-terminal region (ARP40188_P050) in Mouse Muscle using Western Blot

    Gapdh Antibody - C-terminal region (ARP40188_P050)

    Protein Name:Glyceraldehyde-3-phosphate dehydrogenase
    Catalog #:ARP40188_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    GRIK4 Antibody - C-terminal region (ARP35248_P050) in Human THP-1 using Western Blot

    GRIK4 Antibody - C-terminal region (ARP35248_P050)

    Protein Name:Glutamate receptor, ionotropic kainate 4
    Catalog #:ARP35248_P050
    Type: pAb
    Reacts with: Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Grik5 antibody - N-terminal region (ARP35064_P050) in Mouse Pancreas using Western Blot

    Grik5 antibody - N-terminal region (ARP35064_P050)

    Protein Name:Glutamate receptor, ionotropic, kainate 5 (Gamma 2) EMBL AAH52009.2
    Catalog #:ARP35064_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    GHSR antibody - C-terminal region (ARP63610_P050) in Human Jurkat using Western Blot

    GHSR antibody - C-terminal region (ARP63610_P050)

    Protein Name:CRF2 recepter isoform F EMBL ABV59315.1
    Catalog #:ARP63610_P050
    Type: pAb
    Reacts with: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Gcm1 antibody - middle region (ARP36862_P050) in Mouse Heart using Western Blot

    Gcm1 antibody - middle region (ARP36862_P050)

    Protein Name:Chorion-specific transcription factor GCMa
    Catalog #:ARP36862_P050
    Type: pAb
    Reacts with: Mouse, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    GBX2 antibody - middle region (ARP32552_P050) in Human Spleen using Western Blot

    GBX2 antibody - middle region (ARP32552_P050)

    Protein Name:Homeobox protein GBX-2
    Catalog #:ARP32552_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00

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Showing 1 - 30 of 132