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Now Offering Over 48,216 Antibodies & 21,887 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

ARP46323_CENP-M CENPM Antibody
ARP57258_CENP-N CENPN Antibody
ARP30312_TP53 TP53 Antibody
ARP38253_P050-STAT3-IHC-01 STAT3 Antibody
ARP37894_P050_TGF-beta-1 TGFB1 Antibody
ARP30947_PAX7_IF_image_01 PAX7 Antibody
ARP41404_CYP1A1_IHC_image_01 CYP1A1 Antibody
ARP33326_SOX10 SOX10 Antibody
ARP45222_P050_HMOX1_WB_imag HMOX1 Antibody
ARP32548-p50-GATA3-IF-img-0 GATA3 Antibody
ARP32372-HES1-WB-01 HES1 Antibody
ARP37018-ATF4-IF-image-01 ATF4 Antibody
ARP48127_CD36 CD36 Antibody
ARP31400-TFAM-WB-04 TFAM Antibody
ARP32752_OLIG2 Nterm OLIG2 N term Antibody
ARP31859-p50-GATA6-IF-img-02 GATA6 Antibody
ARP33090_T100_MMP9 MMP9 Antibody
AVARP20016_T100_MMP-2 MMP2 Antibody
AVARP20010_KDR KDR Antibody
ARP41456-MUC1-IHC-image-01 MUC1 Antibody

Polyclonal Antibody - Transcription Factors

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 123
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30004_T100 GAS7 antibody - N-terminal region (ARP30004_T100)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Rabbit, Mouse, Rat
Application
WB, IHC
 $229.00
  pAb ARP30036_T100 GLIS2 antibody - N-terminal region (ARP30036_T100)
Reacts with
Human, Dog, Guinea pig, Rat, Mouse, Horse
Application
WB
 $229.00
  pAb ARP30037_P050 GLIS2 antibody - N-terminal region (ARP30037_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, African clawed frog, Chicken, Mouse, Rat
Application
WB, IHC
 $289.00
  pAb ARP30093_P050 GFI1B antibody - N-terminal region (ARP30093_P050)
Reacts with
Dog, Horse, Human, Pig, Bovine, Mouse, Rat
Application
WB, IHC
 $289.00
  pAb ARP31186_P050 Gabpa Antibody - N-terminal region (ARP31186_P050)
Reacts with
Application
WB
 $289.00
  pAb ARP31189_P050 GABPB2 antibody - middle region (ARP31189_P050)
Reacts with
Chicken, Zebrafish
Application
WB
 $289.00
  pAb ARP31333_P050 GTF2A1 antibody - C-terminal region (ARP31333_P050)
Reacts with
Chicken, Horse, Human, Mouse, Rabbit, Rat, Sheep, Dog, African clawed frog, Zebrafish
Application
WB
 $289.00
  pAb ARP31434_P050 GTF2E2 antibody - N-terminal region (ARP31434_P050)
Reacts with
Human, Pig, Mouse, Rat, Zebrafish, Goat
Application
WB
 $289.00
  pAb ARP31436_P050 GTF2F2 antibody - C-terminal region (ARP31436_P050)
Reacts with
Dog, Mouse, Rat, Zebrafish, Chicken
Application
WB, IHC
 $289.00
  pAb ARP31437_P050 GTF2F2 antibody - middle region (ARP31437_P050)
Reacts with
Dog, Mouse, Rat, Chicken, Zebrafish
Application
WB, IHC
 $289.00
  pAb ARP31437_T100 GTF2F2 antibody - middle region (ARP31437_T100)
Reacts with
Dog, Mouse, Rat, Chicken, Zebrafish
Application
WB, IHC
 $229.00
  pAb ARP31438_P050 GTF2H3 antibody - N-terminal region (ARP31438_P050)
Reacts with
Human, Mouse, Pig, Guinea pig
Application
WB, IHC
 $289.00
  pAb ARP31627_P050 GATA5 antibody - middle region (ARP31627_P050)
Reacts with
Human, Bovine, Dog, Guinea pig, Horse, Pig, Sheep, Mouse, Rat
Application
WB
 $289.00
  pAb ARP31662_P050 GSX1 antibody - N-terminal region (ARP31662_P050)
Reacts with
Bovine, Dog, Human, Mouse, Pig, Rabbit, Rat
Application
WB
 $289.00
  pAb ARP31855_T100 GATA2 antibody - N-terminal region (ARP31855_T100)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rat, African clawed frog, Chicken
Application
WB, IHC
 $229.00
  pAb ARP31857_P050 GATA3 antibody - N-terminal region (ARP31857_P050)
Reacts with
Bovine, Chicken, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep, Guinea pig, Zebrafish
Application
WB, IHC
 $289.00
  pAb ARP31859_P050 GATA6 antibody - middle region (ARP31859_P050)
Reacts with
Horse, Human, Pig, Rabbit, Sheep, Bovine, Rat, Guinea pig, Chicken, Mouse
Application
WB, IF, IHC
 $289.00
  pAb ARP31862_T100 GBX2 antibody - middle region (ARP31862_T100)
Reacts with
Bovine, Dog, Human, Rabbit, Guinea pig, Pig, Mouse, Rat
Application
WB
 $229.00
  pAb ARP31869_P050 GFI1 antibody - N-terminal region (ARP31869_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
 $289.00
  pAb ARP31885_T100 GLI2 antibody - N-terminal region (ARP31885_T100)
Reacts with
Human
Application
WB, IHC
 $229.00
  pAb ARP31909_P050 GTF2H4 antibody - N-terminal region (ARP31909_P050)
Reacts with
Bovine, Goat, Guinea pig, Human, Mouse, Pig, Rat
Application
WB
 $289.00
  pAb ARP31910_P050 GTF2I antibody - N-terminal region (ARP31910_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rat, Chicken
Application
WB, IHC
 $289.00
  pAb ARP31910_T100 GTF2I antibody - N-terminal region (ARP31910_T100)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rat, Chicken
Application
WB
 $229.00
  pAb ARP31914_P050 GTF3C2 antibody - middle region (ARP31914_P050)
Reacts with
Human, Dog, Horse, Bovine, Guinea pig, Rabbit
Application
WB
 $289.00
  pAb ARP31917_P050 GRHL1 antibody - N-terminal region (ARP31917_P050)
Reacts with
Bovine, Dog, Horse, Human, Mouse, Rat
Application
WB
 $289.00
  pAb ARP32174_P050 GSC antibody - N-terminal region (ARP32174_P050)
Reacts with
Human, Dog, Mouse, Rat
Application
WB, IHC
 $289.00
  pAb ARP32208_P050 GSH2 antibody - N-terminal region (ARP32208_P050)
Reacts with
Dog, Human, Rat, Mouse
Application
WB, IHC
 $289.00
  pAb ARP32368_T100 GLI1 antibody - C-terminal region (ARP32368_T100)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Rabbit, Mouse, Rat
Application
WB
 $229.00
  pAb ARP32548_P050 GATA3 antibody - C-terminal region (ARP32548_P050)
Reacts with
Human, Bovine, Chicken, Dog, Guinea pig, Horse, Mouse, Pig, Rabbit, Rat, Sheep, African clawed frog
Application
WB, IHC, IF
 $289.00
  pAb ARP32548_T100 GATA3 antibody - C-terminal region (ARP32548_T100)
Reacts with
Human, Bovine, Chicken, Dog, Guinea pig, Horse, Mouse, Pig, Rabbit, Rat, Sheep, African clawed frog
Application
WB
 $229.00

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Showing 1 - 30 of 123

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