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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 127
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30004_T100 GAS7 antibody - N-terminal region (ARP30004_T100)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP30036_T100 GLIS2 antibody - N-terminal region (ARP30036_T100)
Reacts with
Human, Dog, Rat, Guinea pig, Rabbit, Mouse, Horse
Application
WB
$229.00
  pAb ARP30037_P050 GLIS2 antibody - N-terminal region (ARP30037_P050)
Reacts with
Bovine, Dog, Horse, Rat, Guinea pig, Human, Zebrafish, Rabbit, Mouse
Application
IHC, WB
$289.00
  pAb ARP30093_P050 GFI1B antibody - N-terminal region (ARP30093_P050)
Reacts with
Dog, Horse, Human, Pig, Mouse, Goat, Bovine, Rat
Application
IHC, WB
$289.00
  pAb ARP31186_P050 Gabpa Antibody - N-terminal region (ARP31186_P050)
Reacts with
Human, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse, Bovine
Application
WB
$289.00
  pAb ARP31189_P050 GABPB2 antibody - middle region (ARP31189_P050)
Reacts with
Human, Dog, Rat, Pig, Horse, Rabbit, Guinea pig, Mouse, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP31333_P050 GTF2A1 antibody - C-terminal region (ARP31333_P050)
Reacts with
Bovine, Pig, Sheep, Horse, Rabbit, Rat, Human, Mouse, Dog, Guinea pig, Yeast, Zebrafish
Application
WB
$289.00
  pAb ARP31434_P050 GTF2E2 antibody - N-terminal region (ARP31434_P050)
Reacts with
Dog, Human, Bovine, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish, Goat
Application
WB
$289.00
  pAb ARP31436_P050 GTF2F2 antibody - C-terminal region (ARP31436_P050)
Reacts with
Human, Horse, Rabbit, Rat, Guinea pig, Zebrafish, Bovine, Mouse, Dog
Application
IHC, WB
$289.00
  pAb ARP31437_P050 GTF2F2 antibody - middle region (ARP31437_P050)
Reacts with
Dog, Horse, Rabbit, Rat, Guinea pig, Human, Bovine, Mouse, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP31437_T100 GTF2F2 antibody - middle region (ARP31437_T100)
Reacts with
Dog, Horse, Rabbit, Rat, Guinea pig, Human, Bovine, Mouse, Zebrafish
Application
IHC, WB
$229.00
  pAb ARP31438_P050 GTF2H3 antibody - N-terminal region (ARP31438_P050)
Reacts with
Human, Pig, Horse, Rabbit, Mouse, Rat, Bovine, Guinea pig
Application
IHC, WB
$289.00
  pAb ARP31627_P050 GATA5 antibody - middle region (ARP31627_P050)
Reacts with
Human, Dog, Pig, Horse, Sheep, Guinea pig, Bovine, Rat, Mouse
Application
WB
$289.00
  pAb ARP31662_P050 GSX1 antibody - N-terminal region (ARP31662_P050)
Reacts with
Bovine, Mouse, Dog, Pig, Rabbit, Rat, Human, Horse
Application
WB
$289.00
  pAb ARP31855_T100 GATA2 antibody - N-terminal region (ARP31855_T100)
Reacts with
Rat, Human, Bovine, Dog, Horse, Rabbit, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP31857_P050 GATA3 antibody - N-terminal region (ARP31857_P050)
Reacts with
Human, Dog, Pig, Mouse, Horse, Sheep, Rabbit, Rat, Bovine, Guinea pig, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP31859_P050 GATA6 antibody - middle region (ARP31859_P050)
Reacts with
Horse, Human, Pig, Sheep, Rabbit, Rat, Bovine, Guinea pig, Mouse
Application
IF, IHC, WB
$289.00
  pAb ARP31862_T100 GBX2 antibody - middle region (ARP31862_T100)
Reacts with
Pig, Bovine, Dog, Horse, Rabbit, Rat, Human, Guinea pig, Mouse
Application
WB
$229.00
  pAb ARP31869_P050 GFI1 antibody - N-terminal region (ARP31869_P050)
Reacts with
Human, Bovine, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Dog
Application
WB
$289.00
  pAb ARP31885_T100 GLI2 antibody - middle region (ARP31885_T100)
Reacts with
Human
Application
IHC, WB
$229.00
  pAb ARP31909_P050 GTF2H4 antibody - N-terminal region (ARP31909_P050)
Reacts with
Human, Bovine, Mouse, Dog, Horse, Goat, Rat, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP31910_P050 GTF2I antibody - N-terminal region (ARP31910_P050)
Reacts with
Bovine, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
IHC, WB
$289.00
  pAb ARP31910_T100 GTF2I antibody - N-terminal region (ARP31910_T100)
Reacts with
Bovine, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP31914_P050 GTF3C2 antibody - middle region (ARP31914_P050)
Reacts with
Human, Dog, Horse, Bovine, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP31917_P050 GRHL1 antibody - N-terminal region (ARP31917_P050)
Reacts with
Human, Rat, Dog, Mouse, Horse, Bovine, Pig
Application
WB
$289.00
  pAb ARP32174_P050 GSC antibody - N-terminal region (ARP32174_P050)
Reacts with
Pig, Human, Dog, Bovine, Rat, Mouse
Application
IHC, WB
$289.00
  pAb ARP32208_P050 GSH2 antibody - N-terminal region (ARP32208_P050)
Reacts with
Human, Dog, Pig, Horse, Rabbit, Bovine, Rat, Mouse, Guinea pig
Application
IHC, WB
$289.00
  pAb ARP32354_P050 Gps1 Antibody - N-terminal region (ARP32354_P050)
Reacts with
Zebrafish, Bovine, Human, Mouse, Dog, Horse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP32368_T100 GLI1 antibody - C-terminal region (ARP32368_T100)
Reacts with
Bovine, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$229.00
  pAb ARP32548_P050 GATA3 antibody - C-terminal region (ARP32548_P050)
Reacts with
Human, Dog, Pig, Horse, Sheep, Rabbit, Rat, Guinea pig, Mouse, Bovine
Application
IF, IHC, WB
$289.00

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Showing 1 - 30 of 127