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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 130
  Type Catalog # Product Product Images Price (USD)
  pAb ARP73870_P050 GFI1 Antibody - N-terminal region (ARP73870_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP58089_P050 GCFC2 Antibody - N-terminal region (ARP58089_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30176_P050 GRP78 Antibody - C-terminal region (ARP30176_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30036_T100 GLIS2 antibody - N-terminal region (ARP30036_T100)
Reacts with
Human, Dog, Rat, Guinea pig, Rabbit, Mouse, Horse
Application
WB
$229.00
  pAb ARP30037_P050 GLIS2 antibody - N-terminal region (ARP30037_P050)
Reacts with
Bovine, Dog, Horse, Rat, Guinea pig, Human, Zebrafish, Rabbit, Mouse
Application
IHC, WB
$289.00
  pAb ARP57999_P050 GPS1 antibody - N-terminal region (ARP57999_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32354_P050 Gps1 Antibody - N-terminal region (ARP32354_P050)
Reacts with
Zebrafish, Bovine, Human, Mouse, Dog, Horse, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP72751_P050 GCM2 Antibody - N-terminal region (ARP72751_P050)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Zebrafish, Mouse
Application
WB
$289.00
  pAb ARP35520_P050 Gm6185 antibody - middle region (ARP35520_P050)
Reacts with
Human, Rat, Horse, Rabbit, Guinea pig, Dog, Bovine
Application
WB
$289.00
  pAb ARP61198_P050 GET4 antibody - N-terminal region (ARP61198_P050)
Reacts with
Human, Mouse, Rat, Dog, Guinea pig, Horse, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP55987_P050 Gtf2h5 antibody - N-terminal region (ARP55987_P050)
Reacts with
Rat, Dog, Pig, Rabbit, Guinea pig, Bovine, Human, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP31186_P050 Gabpa Antibody - N-terminal region (ARP31186_P050)
Reacts with
Human, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse, Bovine
Application
WB
$289.00
  pAb ARP39430_P050 Gatad2b antibody - C-terminal region (ARP39430_P050)
Reacts with
Human, Mouse, Bovine, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP41763_P050 GH1 antibody - C-terminal region (ARP41763_P050)
Reacts with
Goat, Sheep, Bovine, Human, Rat, Pig, Horse, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP64456_P050 GPRC6A antibody - C-terminal region (ARP64456_P050)
Reacts with
Human, Horse, Yeast, Dog
Application
WB
$289.00
  pAb ARP34734_P050 GREB1 Antibody - N-terminal region (ARP34734_P050)
Reacts with
Bovine, Dog, Horse, Rabbit, Human, Mouse, Pig, Zebrafish, Rat, Guinea pig
Application
WB
$289.00
  pAb ARP35063_P050 Glra3 antibody - middle region (ARP35063_P050)
Reacts with
Human, Rat, Dog, Pig, Horse, Rabbit, Bovine, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP38950_P050 Gtf3c3 antibody - C-terminal region (ARP38950_P050)
Reacts with
Human, Rat, Dog, Pig, Horse, Rabbit, Mouse, Bovine, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP63896_P050 GDAP1 antibody - C-terminal region (ARP63896_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP70505_P050 GREB1 Antibody - N-terminal region (ARP70505_P050)
Reacts with
Mouse, Bovine, Dog, Rat, Pig, Horse, Human, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP48554_P050 GSTA4 antibody - N-terminal region (ARP48554_P050)
Reacts with
Human, Dog, Pig, Rabbit, Bovine, Horse, Guinea pig
Application
WB
$289.00
  pAb ARP64827_P050 GPR50 antibody - C-terminal region (ARP64827_P050)
Reacts with
Human, Pig, Bovine, Rat, Mouse
Application
WB
$289.00
  pAb ARP40188_P050 Gapdh Antibody - C-terminal region (ARP40188_P050)
Reacts with
Bovine, Rat, Horse, Rabbit, Guinea pig, Human, Dog, Mouse
Application
WB
$289.00
  pAb ARP35248_P050 GRIK4 Antibody - C-terminal region (ARP35248_P050)
Reacts with
Human, Dog, Pig, Rabbit, Guinea pig, Rat, Mouse, Horse
Application
WB
$289.00
  pAb ARP35064_P050 Grik5 antibody - N-terminal region (ARP35064_P050)
Reacts with
Dog, Pig, Rabbit, Rat, Guinea pig, Human, Mouse, Bovine, Horse
Application
WB
$289.00
  pAb ARP63610_P050 GHSR antibody - C-terminal region (ARP63610_P050)
Reacts with
Rabbit, Dog, Bovine, Goat, Horse, Guinea pig, Rat, Mouse, Sheep, Human
Application
WB
$289.00
  pAb ARP36862_P050 Gcm1 antibody - middle region (ARP36862_P050)
Reacts with
Mouse, Rat
Application
WB
$289.00
  pAb ARP32552_P050 GBX2 antibody - middle region (ARP32552_P050)
Reacts with
Rat, Pig, Rabbit, Guinea pig, Mouse, Human, Bovine, Dog, Horse
Application
WB
$289.00
  pAb ARP63933_P050 GIPR antibody - N-terminal region (ARP63933_P050)
Reacts with
Human, Rabbit, Rat, Guinea pig, Mouse, Bovine, Dog, Horse
Application
WB
$289.00
  pAb ARP58156_P050 GTF2A1 antibody - middle region (ARP58156_P050)
Reacts with
Bovine, Pig, Sheep, Horse, Rabbit, Rat, Human, Mouse, Yeast, Dog, Guinea pig
Application
WB
$289.00

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Showing 1 - 30 of 130