website statistics

Aviva Systems Biology

Account Login 

Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

Page of 6

Showing 1 - 30 of 153
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30074_P050 EEA1 antibody - N-terminal region (ARP30074_P050)
Reacts with
Human, Rat, Bovine, Horse, Guinea pig, Mouse, Rabbit, Dog
Application
IHC, IP, WB
$289.00
  pAb ARP30096_P050 EOMES antibody - N-terminal region (ARP30096_P050)
Reacts with
Human, Mouse, Rabbit, Dog, Bovine, Pig, Horse, Guinea pig, Rat
Application
WB
$289.00
  pAb ARP30105_T100 ELL antibody - C-terminal region (ARP30105_T100)
Reacts with
Human, Bovine, Dog, Horse, Rat, Zebrafish, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP30106_P050 ELL antibody - middle region (ARP30106_P050)
Reacts with
Human, Dog
Application
WB
$289.00
  pAb ARP31085_P050 ELF1 antibody - N-terminal region (ARP31085_P050)
Reacts with
Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Human, Mouse
Application
IHC, WB
$289.00
  pAb ARP31171_P050 E2F1 antibody - middle region (ARP31171_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31175_P050 E2F4 antibody - C-terminal region (ARP31175_P050)
Reacts with
Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Human, Zebrafish, Mouse
Application
IHC, WB
$289.00
  pAb ARP31180_P050 ELK1 antibody - N-terminal region (ARP31180_P050)
Reacts with
Rat, Mouse, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Human
Application
WB
$289.00
  pAb ARP31181_P050 Elk1 antibody - middle region (ARP31181_P050)
Reacts with
Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP31227_P050 ELK4 antibody - C-terminal region (ARP31227_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31542_P050 ERCC8 antibody - C-terminal region (ARP31542_P050)
Reacts with
Human, Dog, Horse, Pig, Rabbit, Rat
Application
IHC, WB
$289.00
  pAb ARP31611_P050 E2F2 antibody - middle region (ARP31611_P050)
Reacts with
Bovine, Dog, Horse, Human, Rat, Guinea pig, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP31612_P050 E2F2 Antibody - middle region (ARP31612_P050)
Reacts with
Rat, Dog, Human, Pig, Mouse, Bovine, Guinea pig, Rabbit, Zebrafish
Application
WB
$289.00
  pAb ARP31614_P050 EBF1 antibody - N-terminal region (ARP31614_P050)
Reacts with
Zebrafish, Mouse, Human, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP31638_P050 ELF2 antibody - N-terminal region (ARP31638_P050)
Reacts with
Human, Dog, Bovine, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP31639_P050 Elf3 antibody - middle region (ARP31639_P050)
Reacts with
Rabbit, Human, Pig, Horse, Bovine, Dog
Application
WB
$289.00
  pAb ARP31640_P050 ELF4 antibody - N-terminal region (ARP31640_P050)
Reacts with
Dog, Pig, Horse, Rat, Guinea pig, Human, Bovine, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP31643_P050 EMX2 Antibody - N-terminal region (ARP31643_P050)
Reacts with
Rat, Dog, Pig, Rabbit, Guinea pig, Human, Mouse, Bovine, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP31651_P050 ERF antibody - C-terminal region (ARP31651_P050)
Reacts with
Human, Rat, Bovine, Horse, Pig, Dog, Mouse, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP31652_P050 ESR2 antibody - N-terminal region (ARP31652_P050)
Reacts with
Pig, Rat, Human, Mouse, Bovine, Goat, Dog, Guinea pig, Sheep, Rabbit, Horse
Application
WB
$289.00
  pAb ARP31652_T100 ESR2 antibody - N-terminal region (ARP31652_T100)
Reacts with
Pig, Rat, Human, Mouse, Bovine, Goat, Dog, Guinea pig, Sheep, Rabbit, Horse
Application
WB
$229.00
  pAb ARP31654_P050 ESRRB antibody - N-terminal region (ARP31654_P050)
Reacts with
Mouse, Dog, Human, Bovine, Pig, Horse, Rat, Guinea pig, Rabbit
Application
WB
$289.00
  pAb ARP31655_T100 ESRRG antibody - middle region (ARP31655_T100)
Reacts with
Human, Bovine, Dog, Zebrafish, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
IHC, WB
$229.00
  pAb ARP31658_P050 ETV5 antibody - N-terminal region (ARP31658_P050)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP31659_P050 EVI1 antibody - C-terminal region (ARP31659_P050)
Reacts with
Human, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig, Mouse
Application
IHC, WB
$289.00
  pAb ARP31861_T100 EHF antibody - N-terminal region (ARP31861_T100)
Reacts with
Human, Pig, Horse, Rabbit, Rat, Sheep, Dog, Bovine, Mouse, Guinea pig
Application
IHC, WB
$229.00
  pAb ARP31982_T100 EVX2 antibody - N-terminal region (ARP31982_T100)
Reacts with
Human, Rat, Dog, Horse, Mouse, Guinea pig
Application
WB
$229.00
  pAb ARP32149_P050 ERCC8 antibody - N-terminal region (ARP32149_P050)
Reacts with
Human, Zebrafish, Mouse, Dog, Pig, Rabbit, Rat, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP32221_P050 E2F6 antibody - middle region (ARP32221_P050)
Reacts with
Rat, Dog, Horse, Human, Pig, Mouse, Bovine, Guinea pig
Application
IHC, WB
$289.00
  pAb ARP32221_T100 E2F6 antibody - middle region (ARP32221_T100)
Reacts with
Rat, Dog, Horse, Human, Pig, Mouse, Bovine, Guinea pig
Application
WB
$229.00

Page of 6

Showing 1 - 30 of 153