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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 155
  Type Catalog # Product Product Images Price (USD)
  pAb ARP72412_P050 EZH1 Antibody - C-terminal region (ARP72412_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP72379_P050 EGR2 Antibody - middle region (ARP72379_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP73834_P050 E2F8 Antibody - C-terminal region (ARP73834_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP72502_P050 ERCC8 Antibody - C-terminal region (ARP72502_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP73058_P050 ENY2 Antibody - N-terminal region (ARP73058_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP74518_P050 ERCC8 Antibody - C-terminal region (ARP74518_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP73837_P050 ELF5 Antibody - C-terminal region (ARP73837_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP31652_T100 ESR2 antibody - N-terminal region (ARP31652_T100)
Reacts with
Pig, Rat, Human, Mouse, Bovine, Goat, Dog, Guinea pig, Sheep, Rabbit, Horse
Application
WB
$229.00
  pAb ARP57966_P050 E2f5 antibody - C-terminal region (ARP57966_P050)
Reacts with
Human, Mouse, Rat, Horse, Dog, Pig, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP38382_P050 EDF1 Antibody - N-terminal region (ARP38382_P050)
Reacts with
Pig, Rat, Dog, Guinea pig, Human, Bovine, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP39975_P050 Eya4 Antibody - N-terminal region (ARP39975_P050)
Reacts with
Human, Rabbit, Guinea pig, Dog, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP64825_P050 EIF3I antibody - middle region (ARP64825_P050)
Reacts with
Dog, Horse, Rabbit, Human, Mouse, Rat, Pig, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP37038_P050 Esr2 Antibody - N-terminal region (ARP37038_P050)
Reacts with
Dog, Mouse, Pig, Goat, Rat, Sheep, Bovine, Horse, Guinea pig, Human, Rabbit
Application
WB
$289.00
  pAb ARP62653_P050 Ell3 Antibody - C-terminal region (ARP62653_P050)
Reacts with
Human, Rabbit, Dog, Bovine, Horse, Rat, Mouse, Pig
Application
WB
$289.00
  pAb ARP48979_P050 ESCO1 antibody - N-terminal region (ARP48979_P050)
Reacts with
Human, Dog, Rat, Horse, Bovine, Pig
Application
WB
$289.00
  pAb ARP66349_P050 ESF1 Antibody - C-terminal region (ARP66349_P050)
Reacts with
Human, Pig, Rabbit, Rat, Dog, Horse
Application
WB
$289.00
  pAb ARP57974_P050 EYA3 Antibody - middle region (ARP57974_P050)
Reacts with
Human, Guinea pig, Sheep, Bovine, Horse, Rat, Rabbit, Mouse
Application
WB
$289.00
  pAb ARP44397_P050 EG546729 antibody - C-terminal region (ARP44397_P050)
Reacts with
Rat, Human, Mouse, Dog, Rabbit, Bovine, Pig, Horse
Application
WB
$289.00
  pAb ARP51732_P050 EBF4 antibody - C-terminal region (ARP51732_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Rabbit, Rat, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP37784_P050 EBF2 Antibody - C-terminal region (ARP37784_P050)
Reacts with
Human, Rat, Bovine, Dog, Pig, Horse, Guinea pig, Mouse, Rabbit, Zebrafish
Application
WB
$289.00
  pAb ARP31612_P050 E2F2 Antibody - middle region (ARP31612_P050)
Reacts with
Rat, Dog, Human, Pig, Mouse, Bovine, Guinea pig, Rabbit, Zebrafish
Application
WB
$289.00
  pAb ARP48260_P050 ERH antibody - middle region (ARP48260_P050)
Reacts with
Rat, Pig, Horse, Rabbit, Mouse, Guinea pig, Dog, Human, Bovine, Zebrafish
Application
WB
$289.00
  pAb ARP32266_P050 EWSR1 Antibody - C-terminal region (ARP32266_P050)
Reacts with
Bovine, Human, Rat, Dog, Pig, Horse, Rabbit, Mouse, Zebrafish, Guinea pig
Application
WB
$289.00
  pAb ARP61529_P050 E2f6 Antibody - middle region (ARP61529_P050)
Reacts with
Human, Dog, Horse, Pig, Bovine, Rat, Guinea pig, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP36709_P050 EIF2AK2 antibody - middle region (ARP36709_P050)
Reacts with
Human, Rabbit, Bovine, Rat, Horse, Mouse, Dog, Pig
Application
WB
$289.00
  pAb ARP34197_P050 EGR3 antibody - middle region (ARP34197_P050)
Reacts with
Pig, Human, Bovine, Dog, Horse, Rabbit, Rat, Guinea pig, Mouse
Application
IHC, WB
$289.00
  pAb ARP39265_T100 ERGIC2 antibody - N-terminal region (ARP39265_T100)
Reacts with
Human, Bovine, Mouse, Dog, Pig, Horse, Rabbit, Rat, Zebrafish, Guinea pig
Application
WB
$229.00
  pAb ARP51071_P050 ELK1P1 antibody - middle region (ARP51071_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32257_P050 ERF antibody - middle region (ARP32257_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP38468_P050 ETV5 antibody - N-terminal region (ARP38468_P050)
Reacts with
Rat, Human, Mouse, Bovine, Dog, Horse, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00

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Showing 1 - 30 of 155