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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

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Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 162
  • TRIAL 
    EWSR1 Antibody - C-terminal region (ARP32266_P050) in Human 721_B using Western Blot
    EWSR1 Antibody - C-terminal region (ARP32266_P050) in human heart using Immunohistochemistry

    EWSR1 Antibody - C-terminal region (ARP32266_P050)

    Protein Name:RNA-binding protein EWS
    Catalog #:ARP32266_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
    Application: WB, IHC
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    EYA3 Antibody - middle region (ARP57974_P050) in Human Thymus Tumor using Western Blot

    EYA3 Antibody - middle region (ARP57974_P050)

    Protein Name:Eyes absent homolog 3
    Catalog #:ARP57974_P050
    Type: pAb
    Reacts with: Cow, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    E2f5 antibody - C-terminal region (ARP57966_P050) in Mouse Pancreas using Western Blot

    E2f5 antibody - C-terminal region (ARP57966_P050)

    Protein Name:Transcription factor E2F5
    Catalog #:ARP57966_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    EDF1 Antibody - N-terminal region (ARP38382_P050) in Human Uterus Tumor using Western Blot

    EDF1 Antibody - N-terminal region (ARP38382_P050)

    Protein Name:Endothelial differentiation-related factor 1
    Catalog #:ARP38382_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Human, Mouse, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    E2F2 Antibody - middle region (ARP31612_P050) in Human PANC1 using Western Blot

    E2F2 Antibody - middle region (ARP31612_P050)

    Protein Name:
    Catalog #:ARP31612_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Eya4 Antibody - N-terminal region (ARP39975_P050) in Mouse Thymus using Western Blot

    Eya4 Antibody - N-terminal region (ARP39975_P050)

    Protein Name:Eyes absent homolog 4
    Catalog #:ARP39975_P050
    Type: pAb
    Reacts with: Dog, Guinea Pig, Human, Mouse, Rabbit, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    EIF3I antibody - middle region (ARP64825_P050) in Human HeLa using Western Blot
    EIF3I antibody - middle region (ARP64825_P050) in Human HeLa using Western Blot

    EIF3I antibody - middle region (ARP64825_P050)

    Protein Name:Eukaryotic translation initiation factor 3 subunit I
    Catalog #:ARP64825_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Esr2 Antibody - N-terminal region (ARP37038_P050) in Mouse Spleen using Western Blot

    Esr2 Antibody - N-terminal region (ARP37038_P050)

    Protein Name:Estrogen receptor beta
    Catalog #:ARP37038_P050
    Type: pAb
    Reacts with: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    E2f6 Antibody - middle region (ARP61529_P050) in Rat Thymus using Western Blot

    E2f6 Antibody - middle region (ARP61529_P050)

    Protein Name:
    Catalog #:ARP61529_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    EG546729 antibody - C-terminal region (ARP44397_P050) in Mouse Intestine using Western Blot

    EG546729 antibody - C-terminal region (ARP44397_P050)

    Protein Name:MCG55178 EMBL EDL42030.1
    Catalog #:ARP44397_P050
    Type: pAb
    Reacts with: Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    EBF4 antibody - C-terminal region (ARP51732_P050) in Human HT1080 using Western Blot

    EBF4 antibody - C-terminal region (ARP51732_P050)

    Protein Name:Transcription factor COE4 Ensembl ENSP00000370022
    Catalog #:ARP51732_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    EBF2 Antibody - C-terminal region (ARP37784_P050) in Human Thymus Tumor using Western Blot

    EBF2 Antibody - C-terminal region (ARP37784_P050)

    Protein Name:Transcription factor COE2
    Catalog #:ARP37784_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00

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Showing 1 - 30 of 162