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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 119
  Type Catalog # Product Product Images Price (USD)
  pAb ARP60159_P050 DAXX Antibody - N-terminal region (ARP60159_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP39744_P050 DMRTD Antibody - N-terminal region (ARP39744_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP34883_P050 DIDO1 Antibody - N-terminal region (ARP34883_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP30991_P050 DMRT1 Antibody - middle region (ARP30991_P050)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Pig, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP60158_P050 DAXX Antibody - C-terminal region (ARP60158_P050)
Reacts with
Human, Horse, Rat, Dog
Application
WB
$289.00
  pAb ARP43698_P050 Dlg3 antibody - N-terminal region (ARP43698_P050)
Reacts with
Mouse, Bovine, Rabbit, Guinea pig, Human, Rat, Dog
Application
WB
$289.00
  pAb ARP38943_P050 Dpf3 antibody - N-terminal region (ARP38943_P050)
Reacts with
Mouse, Pig, Horse, Rabbit, Guinea pig, Human, Rat, Zebrafish
Application
WB
$289.00
  pAb ARP32803_P050 DBI antibody - N-terminal region (ARP32803_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP64603_P050 DMGDH antibody - C-terminal region (ARP64603_P050)
Reacts with
Human, Pig, Rat, Horse
Application
WB
$289.00
  pAb ARP31591_P050 DDIT3 Antibody - N-terminal region (ARP31591_P050)
Reacts with
Horse, Human, Guinea pig, Rabbit, Rat, Mouse, Dog, Goat, Bovine, Sheep
Application
WB
$289.00
  pAb ARP36809_P050 Dbx1 Antibody - C-terminal region (ARP36809_P050)
Reacts with
Mouse, Rat, Dog, Horse, Rabbit, Pig, Yeast, Human, Guinea pig, Bovine
Application
WB
$289.00
  pAb ARP51154_P050 DKFZp686A1782 Antibody - C-terminal region (ARP51154_P050)
Reacts with
Human, Bovine, Horse, Dog, Pig, Rabbit, Rat
Application
WB
$289.00
  pAb ARP61993_P050 DUSP9 antibody - middle region (ARP61993_P050)
Reacts with
Human, Rat, Dog, Horse, Rabbit, Mouse, Guinea pig, Yeast, Bovine
Application
WB
$289.00
  pAb ARP39847_P050 DHRSX antibody - N-terminal region (ARP39847_P050)
Reacts with
Bovine, Human, Rat, Yeast
Application
WB
$289.00
  pAb ARP63910_P050 DIAPH1 antibody - C-terminal region (ARP63910_P050)
Reacts with
Human, Dog, Mouse, Rat, Pig, Rabbit, Bovine
Application
WB
$289.00
  pAb ARP39875_P050 Dmbx1 Antibody - C-terminal region (ARP39875_P050)
Reacts with
Pig, Zebrafish, Rat, Bovine, Horse, Rabbit, Guinea pig, Human, Mouse, Dog
Application
WB
$289.00
  pAb ARP70161_P050 DUX4L4 Antibody - N-terminal region (ARP70161_P050)
Reacts with
Human, Pig, Rat
Application
WB
$289.00
  pAb ARP35763_P050 Dlx6 antibody - C-terminal region (ARP35763_P050)
Reacts with
Rat, Dog, Bovine, Horse, Rabbit, Human, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP36377_P050 DDX23 antibody - C-terminal region (ARP36377_P050)
Reacts with
Bovine, Human, Rat, Mouse, Dog, Horse, Rabbit, Guinea pig, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP56937_P050 Dnajc27 antibody - N-terminal region (ARP56937_P050)
Reacts with
Bovine, Human, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP32426_P050 DACH2 Antibody - C-terminal region (ARP32426_P050)
Reacts with
Human, Horse, Rabbit, Mouse, Dog, Rat, Bovine
Application
WB
$289.00
  pAb ARP36844_P050 DKFZp686H0575 Antibody - C-terminal region (ARP36844_P050)
Reacts with
Mouse, Rat, Human, Dog, Horse
Application
WB
$289.00
  pAb ARP51120_P050 DUX4 Antibody - middle region (ARP51120_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP43555_P050 Dpy19l1 antibody - C-terminal region (ARP43555_P050)
Reacts with
Mouse, Rat, Zebrafish, Bovine, Dog, Horse, Rabbit, Guinea pig, Human
Application
WB
$289.00
  pAb ARP63111_P050 DACT1 antibody - middle region (ARP63111_P050)
Reacts with
Mouse, Human, Rat, Bovine, Pig, Dog, Rabbit, Guinea pig, Zebrafish
Application
WB
$289.00
  pAb ARP36356_P050 DHX16 antibody - N-terminal region (ARP36356_P050)
Reacts with
Human, Bovine, Dog, Pig, Horse, Goat, Rabbit, Mouse, Rat, Guinea pig, Zebrafish, Yeast
Application
WB
$289.00
  pAb ARP64564_P050 DRP2 antibody - middle region (ARP64564_P050)
Reacts with
Human, Horse, Rabbit, Guinea pig, Bovine, Dog, Rat, Mouse
Application
WB
$289.00
  pAb ARP35845_P050 DUX1 Antibody - N-terminal region (ARP35845_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP70162_P050 DUX4L9 Antibody - C-terminal region (ARP70162_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP36411_P050 Dhx38 antibody - N-terminal region (ARP36411_P050)
Reacts with
Human, Rat, Dog, Bovine, Horse, Rabbit, Guinea pig, Mouse, Zebrafish
Application
WB
$289.00

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Showing 1 - 30 of 119