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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 116
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30647_P050 DYRK3 antibody - N-terminal region (ARP30647_P050)
Reacts with
Human, Rat, Guinea pig, Yeast
Application
WB
$289.00
  pAb ARP30648_P050 DYRK3 antibody - N-terminal region (ARP30648_P050)
Reacts with
Human, Mouse
Application
IF, WB
$289.00
  pAb ARP30991_P050 DMRT1 Antibody - middle region (ARP30991_P050)
Reacts with
Human, Bovine, Dog, Horse, Rabbit, Rat, Pig, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP31488_P050 DRAP1 antibody - N-terminal region (ARP31488_P050)
Reacts with
Rat, Human, Mouse, Zebrafish, Pig, Horse, Goat, Rabbit, Guinea pig, Dog, Bovine, Yeast
Application
WB
$289.00
  pAb ARP31587_P050 DBP antibody - middle region (ARP31587_P050)
Reacts with
Sheep, Dog, Pig, Horse, Human, Rat, Bovine, Mouse
Application
IHC, WB
$289.00
  pAb ARP31591_P050 DDIT3 Antibody - N-terminal region (ARP31591_P050)
Reacts with
Horse, Human, Guinea pig, Rabbit, Rat, Mouse, Dog, Goat, Bovine, Sheep
Application
WB
$289.00
  pAb ARP31604_T100 DLX2 antibody - N-terminal region (ARP31604_T100)
Reacts with
Human, Guinea pig, Dog, Mouse, Bovine, Horse
Application
IHC, WB
$229.00
  pAb ARP31605_P050 DLX3 antibody - N-terminal region (ARP31605_P050)
Reacts with
Pig, Human, Dog, Horse, Rabbit, Rat, Bovine, Sheep, Mouse, Guinea pig
Application
WB
$289.00
  pAb ARP31606_P050 DLX4 antibody - middle region (ARP31606_P050)
Reacts with
Human, Rat, Mouse
Application
WB
$289.00
  pAb ARP31607_P050 DLX5 antibody - N-terminal region (ARP31607_P050)
Reacts with
Pig, Human, Dog, Horse, Rabbit, Rat, Mouse, Bovine, Guinea pig, Zebrafish
Application
IHC, WB
$289.00
  pAb ARP31616_P050 DMRT2 antibody - N-terminal region (ARP31616_P050)
Reacts with
Bovine, Dog, Pig, Horse, Rabbit, Rat, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP32102_P050 DVL2 antibody - N-terminal region (ARP32102_P050)
Reacts with
Human, Rat, Bovine, Dog, Horse, Rabbit, Guinea pig, Mouse, Zebrafish, Yeast
Application
IHC, WB
$289.00
  pAb ARP32195_P050 DBP antibody - N-terminal region (ARP32195_P050)
Reacts with
Human, Pig, Horse, Guinea pig, Sheep, Dog, Bovine, Mouse, Rat
Application
IHC, WB
$289.00
  pAb ARP32212_T100 DLX2 antibody - C-terminal region (ARP32212_T100)
Reacts with
Bovine, Dog, Pig, Rat, Guinea pig, Mouse, Human
Application
IHC, WB
$229.00
  pAb ARP32213_P050 DLX3 antibody - N-terminal region (ARP32213_P050)
Reacts with
Pig, Bovine, Human, Sheep, Rat, Dog, Horse, Rabbit, Guinea pig, Mouse
Application
IHC, WB
$289.00
  pAb ARP32426_P050 DACH2 Antibody - C-terminal region (ARP32426_P050)
Reacts with
Human, Horse, Rabbit, Mouse, Dog, Rat, Bovine
Application
WB
$289.00
  pAb ARP32803_P050 DBI antibody - N-terminal region (ARP32803_P050)
Reacts with
Human
Application
WB
$289.00
  pAb ARP32866_P050 DLX1 antibody - C-terminal region (ARP32866_P050)
Reacts with
Bovine, Dog, Pig, Horse, Rat, Guinea pig, Human, Mouse, Rabbit
Application
WB
$289.00
  pAb ARP32867_P050 DLX5 antibody - middle region (ARP32867_P050)
Reacts with
Zebrafish, Pig, Human, Rat, Sheep, Dog, Horse, Rabbit, Guinea pig, Mouse, Bovine
Application
IHC, WB
$289.00
  pAb ARP33210_P050 DMRT3 antibody - middle region (ARP33210_P050)
Reacts with
Bovine, Human, Rat, Horse, Rabbit, Guinea pig, Mouse, Dog
Application
WB
$289.00
  pAb ARP33221_P050 DPF2 antibody - middle region (ARP33221_P050)
Reacts with
Goat, Bovine, Rat, Dog, Pig, Horse, Rabbit, Guinea pig, Human, Mouse
Application
WB
$289.00
  pAb ARP33222_P050 DPF2 antibody - middle region (ARP33222_P050)
Reacts with
Dog, Pig, Horse, Rat, Guinea pig, Human, Goat, Bovine, Rabbit, Mouse, Zebrafish
Application
WB
$289.00
  pAb ARP33237_P050 DMRTA1 antibody - middle region (ARP33237_P050)
Reacts with
Human, Horse, Rat, Bovine, Rabbit
Application
WB
$289.00
  pAb ARP33686_P050 DKFZp686M216 Antibody - N-terminal region (ARP33686_P050)
Reacts with
Dog, Zebrafish, Pig, Horse, Rabbit, Bovine, Rat, Guinea pig, Mouse, Human, Sheep
Application
WB
$289.00
  pAb ARP34208_P050 DXYS155E antibody - N-terminal region (ARP34208_P050)
Reacts with
Horse, Dog, Human, Rat
Application
IHC, WB
$289.00
  pAb ARP34293_P050 DPF3 antibody - middle region (ARP34293_P050)
Reacts with
Mouse, Human, Rat, Pig, Horse, Rabbit, Guinea pig, Bovine, Dog
Application
WB
$289.00
  pAb ARP34294_P050 DPF3 antibody - N-terminal region (ARP34294_P050)
Reacts with
Mouse, Human, Rat, Bovine, Dog, Pig, Horse, Rabbit, Guinea pig
Application
WB
$289.00
  pAb ARP34507_P050 DLX4 antibody - middle region (ARP34507_P050)
Reacts with
Pig, Bovine, Rat, Dog, Human, Rabbit, Guinea pig, Mouse
Application
WB
$289.00
  pAb ARP34508_P050 DLX4 antibody - N-terminal region (ARP34508_P050)
Reacts with
Pig, Bovine, Rat, Rabbit, Dog, Mouse, Human, Horse, Zebrafish, Guinea pig
Application
WB
$289.00
  pAb ARP34582_T100 DCP1A antibody - N-terminal region (ARP34582_T100)
Reacts with
Bovine, Rat, Dog, Rabbit, Guinea pig, Human, Mouse, Horse
Application
WB
$229.00

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Showing 1 - 30 of 116