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Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

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Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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  • TRIAL 
    DMRTD Antibody (ARP39744_P050) in Human Fetal Lung using Western Blot

    DMRTD Antibody - N-terminal region (ARP39744_P050)

    Protein Name:
    Catalog #:ARP39744_P050
    Type: pAb
    Reacts with: Human
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    DMBX1 Antibody (ARP32156_P050) in Human 786-0 Whole Cell using Western Blot

    DMBX1 Antibody - middle region (ARP32156_P050)

    Protein Name:Diencephalon/mesencephalon homeobox protein 1
    Catalog #:ARP32156_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 

    DMRT1 Antibody - middle region (ARP30991_P050)

    Protein Name:doublesex- and mab-3-related transcription factor 1
    Catalog #:ARP30991_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    DMGDH antibody - C-terminal region (ARP64603_P050) in Human Fetal liver using Western Blot

    DMGDH antibody - C-terminal region (ARP64603_P050)

    Protein Name:Dimethylglycine dehydrogenase, mitochondrial
    Catalog #:ARP64603_P050
    Type: pAb
    Reacts with: Horse, Human, Pig, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    DDIT3 Antibody - N-terminal region (ARP31591_P050) in Human Stomach Tumor using Western Blot
    DDIT3 antibody - N-terminal region (ARP31591_P050) in human heart tissue using Immunohistochemistry

    DDIT3 Antibody - N-terminal region (ARP31591_P050)

    Protein Name:DNA damage-inducible transcript 3 protein Ensembl ENSP00000447803 Ensembl ENSP00000448665
    Catalog #:ARP31591_P050
    Type: pAb
    Reacts with: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
    Application: WB, IHC
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    DUX1 Antibody - N-terminal region (ARP35845_P050) in Human Esophagus Tumor using Western Blot

    DUX1 Antibody - N-terminal region (ARP35845_P050)

    Protein Name:Double homeobox protein 1
    Catalog #:ARP35845_P050
    Type: pAb
    Reacts with: Human
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    DIAPH1 antibody - C-terminal region (ARP63910_P050) in Human HepG2 using Western Blot

    DIAPH1 antibody - C-terminal region (ARP63910_P050)

    Protein Name:Protein diaphanous homolog 1
    Catalog #:ARP63910_P050
    Type: pAb
    Reacts with: Cow, Dog, Human, Mouse, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Dmbx1 Antibody - C-terminal region (ARP39875_P050) in Mouse Stomach using Western Blot

    Dmbx1 Antibody - C-terminal region (ARP39875_P050)

    Protein Name:Diencephalon/mesencephalon homeobox protein 1
    Catalog #:ARP39875_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    DKFZp686M216 Antibody - N-terminal region (ARP33686_P050) in Human HepG2 using Western Blot

    DKFZp686M216 Antibody - N-terminal region (ARP33686_P050)

    Protein Name:Putative uncharacterized protein DKFZp686M216 EMBL CAD97972.1
    Catalog #:ARP33686_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    DAXX Antibody - C-terminal region (ARP60158_P050) in Human HepG2 using Western Blot

    DAXX Antibody - C-terminal region (ARP60158_P050)

    Protein Name:Death domain-associated protein 6
    Catalog #:ARP60158_P050
    Type: pAb
    Reacts with: Dog, Horse, Human, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Dlx6 antibody - C-terminal region (ARP35763_P050) in Rat Muscle using Western Blot

    Dlx6 antibody - C-terminal region (ARP35763_P050)

    Protein Name:
    Catalog #:ARP35763_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    DDX23 antibody - C-terminal region (ARP36377_P050) in Human Jurkat using Western Blot

    DDX23 antibody - C-terminal region (ARP36377_P050)

    Protein Name:Probable ATP-dependent RNA helicase DDX23
    Catalog #:ARP36377_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Dnajc27 antibody - N-terminal region (ARP56937_P050) in Mouse Kidney using Western Blot

    Dnajc27 antibody - N-terminal region (ARP56937_P050)

    Protein Name:DnaJ homolog subfamily C member 27
    Catalog #:ARP56937_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Dbx1 Antibody - C-terminal region (ARP36809_P050) in Rat Small Intestine using Western Blot

    Dbx1 Antibody - C-terminal region (ARP36809_P050)

    Protein Name:Homeobox protein DBX1
    Catalog #:ARP36809_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    DKFZp686A1782 Antibody - C-terminal region (ARP51154_P050) in Human Fetal Lung using Western Blot

    DKFZp686A1782 Antibody - C-terminal region (ARP51154_P050)

    Protein Name:Putative uncharacterized protein DKFZp686A1782 EMBL CAE45787.1
    Catalog #:ARP51154_P050
    Type: pAb
    Reacts with: Cow, Dog, Horse, Human, Pig, Rabbit, Rat
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    Dpy19l1 antibody - C-terminal region (ARP43555_P050) in Mouse Brain using Western Blot

    Dpy19l1 antibody - C-terminal region (ARP43555_P050)

    Protein Name:Protein dpy-19 homolog 1
    Catalog #:ARP43555_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    DACT1 antibody - middle region (ARP63111_P050) in Human 293T using Western Blot

    DACT1 antibody - middle region (ARP63111_P050)

    Protein Name:Dapper homolog 1
    Catalog #:ARP63111_P050
    Type: pAb
    Reacts with: Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00
  • TRIAL 
    DHX16 antibody - N-terminal region (ARP36356_P050) in Human PANC1 using Western Blot

    DHX16 antibody - N-terminal region (ARP36356_P050)

    Protein Name:cDNA FLJ53577, highly similar to pre-mRNA-splicing factor ATP-dependentRNA helicase DHX16 (EC 3.6.1.-) EMBL BAG63940.1
    Catalog #:ARP36356_P050
    Type: pAb
    Reacts with: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
    Application: WB
    Product Size: 100 ul
    Price (USD): $289.00

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Showing 1 - 30 of 122