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Now Offering Over 48,216 Antibodies & 21,887 Antigens!

Transcription Factor Antibodies

Transcription factors are proteins that regulate gene expression by binding to DNA via one or more DNA-binding domains. This binding is achieved via a combination of electrostatic and van der waals forces and can occur at many closely-related sequences flanking different genes. Once bound to DNA directly or as part of a complex, they can promote or inhibit RNA polymerase recruitment, thereby acting as activators or repressors, respectively. Alternatively, transcription factors can act to recruit coactivators and corepressors or to catalyze histone acetylation and deacetylation. Transcription factors can function downstream of signaling cascades triggered by biological or environmental (ex. hypoxia, hyperthermia) stimuli to alter the expression of target genes. Ligand binding is necessary to activate some transcription factors as this can cause nuclear translocation and changes in the binding affinities for DNA and cofactors. During development, various stimuli can cause transcription factors to up- or down-regulate expression of specific genes at distinct time points to ensure proper development. Transcription factors can function as oncogenes or tumor suppressors and have thus been linked to various cancers. Accordingly, some therapeutic approaches in cancer therapy involve targeting transcription factor families[1].

1. Darnell JE Jr. 2002. Transcription factors as targets for cancer therapy. Nat Rev Cancer. Oct;2(10):740-9.

Transcription Factor Antibodies Top 20 Showcase

View the entire product list by clicking here.

ARP46323_CENP-M CENPM Antibody
ARP57258_CENP-N CENPN Antibody
ARP30312_TP53 TP53 Antibody
ARP38253_P050-STAT3-IHC-01 STAT3 Antibody
ARP37894_P050_TGF-beta-1 TGFB1 Antibody
ARP30947_PAX7_IF_image_01 PAX7 Antibody
ARP41404_CYP1A1_IHC_image_01 CYP1A1 Antibody
ARP33326_SOX10 SOX10 Antibody
ARP45222_P050_HMOX1_WB_imag HMOX1 Antibody
ARP32548-p50-GATA3-IF-img-0 GATA3 Antibody
ARP32372-HES1-WB-01 HES1 Antibody
ARP37018-ATF4-IF-image-01 ATF4 Antibody
ARP48127_CD36 CD36 Antibody
ARP31400-TFAM-WB-04 TFAM Antibody
ARP32752_OLIG2 Nterm OLIG2 N term Antibody
ARP31859-p50-GATA6-IF-img-02 GATA6 Antibody
ARP33090_T100_MMP9 MMP9 Antibody
AVARP20016_T100_MMP-2 MMP2 Antibody
AVARP20010_KDR KDR Antibody
ARP41456-MUC1-IHC-image-01 MUC1 Antibody

Polyclonal Antibody - Transcription Factors

Transcription Factors are involved in transcriptional regulation in the form of up regulation or down regulation acting as either repressors or activators of transcription. We have manufactured more than 3000 antibody products covering almost every known human and mouse transcription factors.

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Showing 1 - 30 of 209
  Type Catalog # Product Product Images Price (USD)
  pAb ARP30002_P050 CBX4 antibody - N-terminal region (ARP30002_P050)
Reacts with
Bovine, Dog, Guinea pig, Human, Mouse, Pig, Rabbit, Chicken, African clawed frog
Application
WB, IHC
 $289.00
  pAb ARP30113_T100 CALR antibody - C-terminal region (ARP30113_T100)
Reacts with
Human, Mouse, Bovine, Rat
Application
WB
 $229.00
  pAb ARP30114_P050 CALR antibody - C-terminal region (ARP30114_P050)
Reacts with
Human, Mouse, Rat, Pig, Rabbit, Zebrafish, African clawed frog
Application
WB
 $289.00
  pAb ARP30259_P050 CDK4 antibody - C-terminal region (ARP30259_P050)
Reacts with
Human, Pig, Dog, Rabbit, Rat
Application
WB
 $289.00
  pAb ARP30331_P050 CDK2 antibody - middle region (ARP30331_P050)
Reacts with
Bovine, Chicken, Goat, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep, Zebrafish
Application
WB
 $289.00
  pAb ARP30416_P050 CRK antibody - C-terminal region (ARP30416_P050)
Reacts with
African clawed frog, Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rat, Chicken
Application
WB
 $289.00
  pAb ARP30645_P050 CLK4 antibody - N-terminal region (ARP30645_P050)
Reacts with
Dog, Human, Pig, Bovine, Chicken, Horse, Mouse, Rat
Application
WB
 $289.00
  pAb ARP30665_P050 CHAT antibody - C-terminal region (ARP30665_P050)
Reacts with
Dog, Human
Application
WB
 $289.00
  pAb ARP30673_P050 CHRNA6 antibody - N-terminal region (ARP30673_P050)
Reacts with
Human, Dog, Chicken, Bovine, Horse, Rabbit, Mouse, Rat
Application
WB
 $289.00
  pAb ARP30775_P050 Ccl20 antibody - C-terminal region (ARP30775_P050)
Reacts with
Human, Chicken, Horse, Mouse, Pig, Dog, Rat
Application
WB
 $289.00
  pAb ARP30901_P050 CBFB Antibody - N-terminal region (ARP30901_P050)
Reacts with
Application
WB
 $289.00
  pAb ARP31259_P050 CEBPB antibody - C-terminal region (ARP31259_P050)
Reacts with
Bovine, Guinea pig, Human, Pig, Rabbit
Application
WB
 $289.00
  pAb ARP31264_T100 CREB1 antibody - N-terminal region (ARP31264_T100)
Reacts with
Horse, Human, Mouse, Rat
Application
WB
 $229.00
  pAb ARP31337_P050 CCNH antibody - N-terminal region (ARP31337_P050)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, African clawed frog, Chicken
Application
WB
 $289.00
  pAb ARP31349_P050 Cyhr1 antibody - middle region (ARP31349_P050)
Reacts with
Dog, Human, Mouse, Rat, Bovine
Application
WB
 $289.00
  pAb ARP31476_P050 CDX2 antibody - middle region (ARP31476_P050)
Reacts with
Chicken, Dog, Human, Mouse, Pig, Rabbit, Rat
Application
WB
 $289.00
  pAb ARP31478_P050 CDX4 antibody - middle region (ARP31478_P050)
Reacts with
Dog, Human, Bovine, Chicken, Mouse, Rat, Zebrafish, African clawed frog
Application
WB, IHC
 $289.00
  pAb ARP31512_P050 COPS5 antibody - N-terminal region (ARP31512_P050)
Reacts with
Dog, Horse, Human, Mouse, Pig, Rat, Bovine, Chicken
Application
WB
 $289.00
  pAb ARP31562_P050 CREBL1 antibody - middle region (ARP31562_P050)
Reacts with
Pig
Application
WB
 $289.00
  pAb ARP31848_T100 C20ORF194 antibody - C-terminal region (ARP31848_T100)
Reacts with
Human, Bovine, Chicken, Dog, Horse
Application
WB
 $229.00
  pAb ARP31932_P050 CSEN antibody - N-terminal region (ARP31932_P050)
Reacts with
Bovine, Human, Mouse, Rat
Application
WB, IHC
 $289.00
  pAb ARP31974_P050 CHX10 antibody - C-terminal region (ARP31974_P050)
Reacts with
Rat
Application
WB
 $289.00
  pAb ARP32048_T100 CNOT2 antibody - middle region (ARP32048_T100)
Reacts with
Bovine, Dog, Guinea pig, Human, Mouse, Pig, Rabbit, Rat, Chicken
Application
WB
 $229.00
  pAb ARP32167_T100 CREBL1 antibody - N-terminal region (ARP32167_T100)
Reacts with
Pig
Application
WB
 $229.00
  pAb ARP32468_P050 CTBP1 antibody - C-terminal region (ARP32468_P050)
Reacts with
Dog, Human, Rat, Chicken, Horse, Mouse, African clawed frog
Application
WB, IHC
 $289.00
  pAb ARP32468_T100 CTBP1 antibody - C-terminal region (ARP32468_T100)
Reacts with
Dog, Human, Rat, Chicken, Horse, Mouse, African clawed frog
Application
WB
 $229.00
  pAb ARP32469_P050 CTBP1 antibody - N-terminal region (ARP32469_P050)
Reacts with
African clawed frog, Bovine, Chicken, Dog, Guinea pig, Horse, Human, Mouse, Rat, Zebrafish
Application
WB
 $289.00
  pAb ARP32481_T100 CBX5 antibody - middle region (ARP32481_T100)
Reacts with
Bovine, Human, Sheep, Dog, Mouse, Rat
Application
WB, IHC
 $229.00
  pAb ARP32498_T100 CIC antibody - N-terminal region (ARP32498_T100)
Reacts with
Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rabbit, Rat
Application
WB, IHC
 $229.00
  pAb ARP32536_T100 CCRN4L antibody - N-terminal region (ARP32536_T100)
Reacts with
Bovine, Horse, Human, Dog, Mouse, Rabbit, Rat
Application
WB, IHC
 $229.00

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Showing 1 - 30 of 209

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