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Now Offering Over 85,203 Antibodies & 34,301 Antigens!

RNA Binding Proteins Antibodies

RNA-binding proteins (RBPs) are critical regulators of RNA metabolism. RBPs play a role in translational regulation and can influence the stability, function, transport, and cellular localization of RNA transcripts[1]. RBPs can bind to both coding and non-coding untranslated RNA via single- or double-stranded RNA-binding motifs to form ribonucleic protein complexes (RNPs). The specific RBP binding domain and the individual RNA sequence determine RBP binding specificity. Single RBPs routinely bind several mRNA transcripts of proteins of similar function. In addition to transcriptional regulation, RNP function can also be attenuated by intra- or extracellular signals via post-translational modifications that affect their ability to sequester specific RNA sequences. More than 500 unique RBPs have been identified in the human genome.

In addition to binding RNA sequences, recent research has identified other roles for RBPs, including acting as substrates for kinases in DNA damage responses and influencing cell attachments through association with focal adhesion kinases[2].

Several human diseases have been linked to genetic defects in RNA-binding proteins. For instance, loss of function of specific RBPs have been associated with spinal muscular atrophy and Fragile X Syndrome. Conversely, RBP gain of function has been associated with myotonic dystrophy and oculopharyngeal muscular dystrophy. Based on the potential influence of RBPs on cell cycle, growth, and proliferation, they are implicated in several different malignancies, including breast and prostate cancers[3].

1. Glisovic et al. 2008. FEBS Lett. RNA-binding proteins and post-transcriptional gene regulation. 582(14):1977-86.
2. Lukong et al. 2008. Trends Genet. RNA-binding proteins in human genetic disease. 24(8):416-25.
3. Keene. 2007. Nature Reviews Genetics. RNA regulons: coordination of post-transcriptional events. 8, 533-543.

Proteins that bind to RNA molecules such as ribonucleic proteins and other proteins whose function is to bind specifically to RNA. These proteins may regulate the translation of RNA, and post-transcriptional events, such as RNA splicing, editing. We have manufactured antibody products for ~700 of these kinds of protein.

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Showing 1 - 30 of 268
  Type Catalog # Product Product Images Price (USD)
  Protein OPSA10624 SYNTHETIC ARG-VASOPRESSIN Purified Protein (1mg)
Reacts with
Application
$135.00
  Protein OPSA10560 SYNTHETIC ALPHA MELANOCYTE STIMULATING HORMONE Purified Protein (0.5mg)
Reacts with
Application
$135.00
  Protein OPSA10545 SYNTHETIC HUMAN KATACALCIN Purified Protein (0.1mg)
Reacts with
Human
Application
$155.00
  Protein OPSA10468 SYNTHETIC HUMAN BMP-7 (aa1-14) Purified Protein (50ug)
Reacts with
Human
Application
$160.00
  OOSA09707 SYNTHETIC RAT CALCITONIN GENE RELATED PEPTIDE Antigen (50ug)
Reacts with
Rat
Application
$190.00
  OOSA09704 SYNTHETIC HUMAN ACTH (aa1-39) Antigen (0.1mg)
Reacts with
Human
Application
$155.00
  Peptide OESA09493 STAT6 BLOCKING PEPTIDE (50ug)
Reacts with
Human
Application
$260.00
  pAb OASA09383 SHEEP ANTI RAT ENDOTHELIN B RECEPTOR (C-TERMINAL) Antibody (0.1mg)
Reacts with
Rat
Application
IF, IP, IHC-FFPE
$325.00
  pAb OASA08812 STAT6 Antibody (OASA08812)
Reacts with
Human
Application
IP, WB
$410.00
  pAb OASA08793 SMAD3 Antibody (OASA08793)
Reacts with
Human
Application
ELISA, IHC-FFPE, WB
$750.00
  pAb OASA08787 SNAI2 Antibody (OASA08787)
Reacts with
Human
Application
WB
$355.00
  pAb OASA08619 Snca Antibody (OASA08619)
Reacts with
Rat
Application
WB
$750.00
  pAb OASA08477 Stat4 Antibody (OASA08477)
Reacts with
Mouse
Application
ELISA, IP, WB
$380.00
  pAb OASA08176 SP1 Antibody (OASA08176)
Reacts with
Human
Application
IP, WB
$735.00
  pAb OASA08169 SMC1A Antibody (OASA08169)
Reacts with
Human
Application
IP, WB
$910.00
  pAb OASA08168 SMC1A Antibody (OASA08168)
Reacts with
Human
Application
IP, WB
$865.00
  pAb OASA06855 STAT3 antibody - C-terminal region (OASA06855)
Reacts with
Human
Application
IHC-AFF, ELISA, WB
$560.00
  pAb OASA06456 STAT1 Antibody (OASA06456)
Reacts with
Human
Application
WB
$560.00
  pAb OASA06449 SMAD2 Antibody (OASA06449)
Reacts with
Human
Application
WB
$545.00
  pAb OASA06014 SNCA Antibody (OASA06014)
Reacts with
Human
Application
ELISA, IHC-FFPE
$400.00
  mAb OASA02329 SELE Antibody (OASA02329)
Reacts with
Human
Application
FC
$440.00
  mAb OASA02328 SELE Antibody (OASA02328)
Reacts with
Human
Application
FC
$500.00
  mAb OASA02327 SELE Antibody (OASA02327)
Reacts with
Human
Application
FC
$100.00
  mAb OASA02326 SELE Antibody (OASA02326)
Reacts with
Human
Application
FC
$355.00
  mAb OASA02325 SELE Antibody (OASA02325)
Reacts with
Human
Application
IHC-AFF, ELISA, FC, IP, WB
$95.00
  mAb OASA02324 SELE Antibody (OASA02324)
Reacts with
Human
Application
IHC-AFF, ELISA, FC, IP, WB
$545.00
  mAb OASA02323 SELE Antibody (OASA02323)
Reacts with
Human
Application
IHC-AFF, FC
$415.00
  mAb OASA01070 SEMA4D Antibody (OASA01070)
Reacts with
Human
Application
FC
$135.00
  mAb OASA01069 SEMA4D Antibody (OASA01069)
Reacts with
Human
Application
FC
$745.00
  mAb OASA01068 SEMA4D Antibody (OASA01068)
Reacts with
Human
Application
FC, IP, WB
$500.00

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Showing 1 - 30 of 268