- Description of Target:
- COLQ encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in COLQ are associated with endplate acetylcholinesterase deficiency.
- Gene Symbol:
- Official Gene Full Name:
- Collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
- NCBI Gene Id:
- Alias Symbols:
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express COLQ.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express COLQ.
- Swissprot Id:
- Protein Accession #:
- Nucleotide Accession #:
- Protein Name:
- Acetylcholinesterase collagenic tail peptide
- Protein Size (# AA):
- Molecular Weight:
- Protein Interactions:
- UBC; MUSK; BCHE; ACHE;
- The immunogen for anti-COLQ antibody: synthetic peptide directed towards the N terminal of human COLQ
- Product Format:
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
- Affinity Purified
- Complete computational species homology data:
- COLQ antibody - N-terminal region (ARP34362_P050)
- Predicted Homology Based on Immunogen Sequence:
- Human: 100%; Rat: 93%; Horse: 93%; Rabbit: 93%; Mouse: 92%; Bovine: 86%
- Species Reactivity:
- Human, Rat, Horse, Rabbit, Mouse, Bovine
- Datasheets / Downloads:
- Printable datasheet for
anti-COLQ antibody- ARP34362_P050
- Peptide Sequence:
- Synthetic peptide located within the following region: LQLFFLSIVSQPTFINSVLPISAALPSLDQKKRGGHKACCLLTPPPPPLF
- Blocking Peptide:
- For anti-COLQ antibody is Catalog # AAP34362 (Previous Catalog # AAPY00137)
- Target Reference:
- Ishigaki,K., et al., (2003) Neuromuscul. Disord. 13 (3), 236-244
- Reconstitution and Storage:
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Aviva Systems Biology is the original manufacturer of this COLQ antibody (ARP34362_P050)
Click here to view the COLQ antibody Western Blot Protocol
Product Datasheet Link: COLQ antibody (ARP34362_P050)
WB Suggested Anti-COLQ Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2
Western Blot image:
Description of Target: COLQ encodes the subunit of a collagen-like molecule associated with acetylcholinesterase in skeletal muscle. Each molecule is composed of three identical subunits. Each subunit contains a proline-rich attachment domain (PRAD) that binds an acetylcholinesterase tetramer to anchor the catalytic subunit of the enzyme to the basal lamina. Mutations in COLQ are associated with endplate acetylcholinesterase deficiency.
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