KCNA5 antibody - N-terminal region (ARP33977_P050)

Catalog#: ARP33977_P050

• Size: 50ug

Human HepG2

• Description of Target: Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). KCNA5 encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion.
• Gene Symbol: KCNA5
• Official Gene Full Name: Potassium voltage-gated channel, shaker-related subfamily, member 5
• Alias Symbols: ATFB7; HCK1; HK2; HPCN1; KV1.5; MGC117058; MGC117059; PCN1
• Protein Accession#: NP_002225
• Nucleotide Accession#: NM_002234
• Swissprot Id: P22460
• Host: Rabbit
• Clonality: Polyclonal
• Protein Size (# AA): 613
• Molecular Weight: 67kDa
• Application: WB
• Partner Proteins: ACTN2, DLG1, DLG4, KCNA2, PTPRE, SRC, ACTN2, DLG1, DLG4, KCNA2
• Immunogen: The immunogen for anti-KCNA5 antibody: synthetic peptide directed towards the N terminal of human KCNA5
• Product Format: Lyophilized powder
• Predicted Homology Based on Immunogen Sequence: Human: 100%; Mouse: 92%; Rat: 92%
• Peptide Sequence: Synthetic peptide located within the following region: DPGVRPLPPLPEELPRPRRPPPEDEEEEGDPGLGTVEDQALGTASLHHQR
• Blocking Peptide: For anti-KCNA5 antibody is Catalog # AAP33977 (Previous Catalog # AAPP05052)
• Key Reference: N/A
• Reconstitution and Storage: Add 50 μl of distilled water. Final anti-KCNA5 antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.