Anti-Mitochondria (OAPC00009)

Catalog No: OAPC00009

Size:100 ul

Western blot of HeLa lysate showing specific immunolabeling of the ~ 60k mitochondrial protein.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. 100 ul liquid.
• Clonality: Monoclonal
• Clone: 113-1
• Isotype: IgG¹
• Host: Mouse
• Application: WB, IF, IHC
• Additional Information: Packaging :
  100 ul liquid.
• Reconstitution and Storage: Store at -20C in undiluted aliquots; stable for up to one year after date of receipt. Avoid freeze/thaw cycles.
• Immunogen: Human cell homogenate
• Purification: Total IgG fraction
• Predicted Homology Based on Immunogen Sequence: Human
• Specificity: Specific for human mitochondria in all cell types. The antibody works on acetone fixed and 2% paraformaldehyde fixed cells. The antibody also works for immunohistochemistry on 2% paraformaldehyde fixed (5-10 minutes) cryostat sections.
• Application Info: The antibody has been directly tested for reactivity in human tissue. It does not react with mouse or rat mitochondria.
  Western blot of HeLa lysate showing specific immunolabeling of the ~ 60k mitochondrial protein.
  
• Reference: McBride HM, Neuspiel M, Wasiak S (2006) Mitochondria: More than just a powerhouse. Curr Biol. 16(14):R551-60
  Green DR (1998) Apoptotic pathways: the roads to ruin. Cell 94(6):695-8.

Target Info

• Description of Target: Mitochondria are most commonly known as the power plants of the cell as they produce ATP, but they are also involved in many other important cellular processes such as cell signaling, growth and differentiation (McBride et al., 2006). In addition, mitochondria have been shown to play a role in apoptosis (Green 1998). This antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.