- Description of Target:
- This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.
- Gene Symbol:
- PROC
- Alias Symbols:
- PC; APC; PROC1; THPH3; THPH4
- Tissue Tool:
- Find tissues and cell lines supported to express PROC.
- Protein Accession# :
- NP_000303
- Nucleotide Accession#:
- NM_000312
- Swissprot Id:
- P04070
- Host:
- Mouse
- Protein Size (# AA):
- 461
- Molecular Weight:
- 52
- Application:
- WB
- Clone:
- 10D6
- Product Format:
- Lyophilized powder
- Isotype:
- IgG1
- Reconstitution and Storage:
- Add 100ul of distilled water. Final anti-PROC antibody concentration is 1 mg/ml in PBS buffer. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
- Key Reference:
- N/A
- Datasheets / Downloads:
- Printable datasheet for
anti-PROC antibody
- AMM10311A
- Protocol:
- Tips Information:
See our General FAQ page.
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