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- Description of Target:
- This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
- Gene Symbol:
- Nucleotide Accession#:
- This plasmid may represent the whole or partial sequence of the target. Inquire to email@example.com for more information.
- Reconstitution and Storage:
- Centrifuge the vials after receiving and add 5 μl ddH2O
- Key Reference:
- Datasheets / Downloads: