CDK9 (Human) cDNA (1ug)

Catalog#: ANA00002-P001

• Size: 1ug

• Description of Target: CDK9 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
• Gene Symbol: CDK9
• Alias Symbols: RP11-228B15.5; C-2k; CDC2L4; PITALRE; TAK; CTK1
• Protein Accession#: NP_001252
• Nucleotide Accession#: NM_001261
• Swissprot Id: P50750
• Sequence: This plasmid may represent the whole or partial sequence of the target. Inquire to techsupport@avivasysbio.com for more information.
• Tag: None
• Reconstitution and Storage: Already in solution (1 ug/ul). For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
• Key Reference: Li,Q., (2005) J. Biol. Chem. 280 (31), 28819-28826