- Description of Target:
- The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.
- Gene Symbol:
- PKLR
- Nucleotide Accession#:
- BC025737
- Sequence:
- This plasmid may represent the whole or partial sequence of the target. Inquire to techsupport@avivasysbio.com for more information.
- Tag:
- None
- Reconstitution and Storage:
- Centrifuge the vials after receiving and add 5 μl ddH2O
- Key Reference:
- N/A
- Datasheets / Downloads:
- ANA11288
- Protocol:
- Tips Information:
- Please see our FAQ
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