PHAP Antibody (OAPB00198)

Catalog No: OAPB00198 (Formerly GWB-2245AA)

Size:100UG

Click here to learn more about Aviva's By-Request Conjugation Service.

Western blot analysis of PHAP expression in human Raji cell llysate with PHAP antibody at 1 μg/mL.

Immunohistochemistry of PHAP in human small intestine tissue with PHAP antibody at 10 μg/mL.

Immunofluorescence of PHAP in human small intestine tissue with PHAP antibody at 20 μg/mL.

Product Info

• Predicted Species Reactivity: Bovine|Human|Mouse|Rat
• Product Format: Liquid. PHAP Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: PHAP antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: PHAP antibody was raised with a synthetic peptide corresponding to amino acids at carboxy terminus of human PHAP I. The immunogen is located within the last 50 amino acids of PHAP.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-PHAP antibody is Catalog # OEPB02294
• Application Info: PHAP antibody can be used for detection of PHAP I and PHAP III by Western blot at 0.5 to 2 ug/ml. At approximately 35 kDa and 32 kDa a band can be detected. (Optimal dilution should be determined by user)
• Reference:  Jiang X, Kim HE, Shu H, Zhao Y, Zhang H, Kofron J, Donnelly J, Burns D, Ng SC , Rosenberg S, Wang X. Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science. 2003;299(5604):223-6.;Nicholson DW, Thornberry NA. Apoptosis. Life and death decisions. Science. 2003 10;299(5604):214-5.;

Target Info

• Gene Symbol: ANP32A
• Gene Full Name: acidic nuclear phosphoprotein 32 family member A
• Alias Symbols: acidic (leucine-rich) nuclear phosphoprotein 32 family, member A;acidic leucine-rich nuclear phosphoprotein 32 family member A;acidic nuclear phosphoprotein pp32;C15orf1;cerebellar leucine rich acidic nuclear protein;epididymis secretory sperm binding protein;hepatopoietin Cn;HPPCn;I1PP2A;inhibitor-1 of protein phosphatase-2A;LANP;leucine-rich acidic nuclear protein;MAPM;mapmodulin;PHAP1;PHAPI;potent heat-stable protein phosphatase 2A inhibitor I1PP2A;PP32;putative HLA-DR-associated protein I;putative human HLA class II associated protein I.
• NCBI Gene Id: 8125
• Protein Name: Acidic leucine-rich nuclear phosphoprotein 32 family member A
• Description of Target: Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.
• Uniprot ID: P39687
• Protein Accession #: P39687
• Molecular Weight: 35 kDa