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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
Datasheets/Manuals | Printable datasheet for anti-PDE4D antibody - OAGA00330 |
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Predicted Species Reactivity | Human |
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Product Format | Liquid. In 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Application | ICC, IF, IHC-FFPE, WB |
Additional Information | Positive Controls: A431, HeLa |
:: | Cellular Localization: Cytoplasm (By similarity), Membrane (By similarity), Cytoplasm, cytoskeleton (By similarity), Centrosome (By similarity) |
Reconstitution and Storage | Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PDE4D. The exact sequence is proprietary. |
Purification | Purified by antigen-affinity chromatography. |
Concentration | 0.3 mg/ml |
Application Info | Suggested starting dilutions are as follows: WB: 1:500-1:3000, IHC-P: 1:100-1:1000 [suggested antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)], ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. Positive Controls: A431 , HeLa |
Publications | Inactivation of oncogenic cAMP-specific phosphodiesterase 4D by miR-139-5p in response to p53 activation. Elife. 5, (2016). 27383270 |
Gene Symbol | PDE4D |
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Gene Full Name | cAMP-specific 3',5'-cyclic phosphodiesterase 4D |
Alias Symbols | DPDE3, PDE43, STRK1, ACRDYS2, HSPDE4D, PDE4DN2 |
NCBI Gene Id | 5144 |
Protein Name | cAMP-specific 3',5'-cyclic phosphodiesterase 4D |
Description of Target | The PDE4D gene is complex and has at least 9 different isoforms that encode functional proteins. These proteins degrade the second messenger cAMP, which is a key signal transduction molecule in multiple cell types, including vascular cells (Dominiczak and McBride, 2003 [PubMed 14517535]).[supplied by OMIM] |
Uniprot ID | Q08499 |
Protein Accession # | NP_001098101.1 |
Molecular Weight | 91 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PDE4D Antibody (OAGA00330)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "PDE4D Antibody (OAGA00330)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "PDE4D Antibody (OAGA00330)" provided in?
This item is provided in "Liquid. In 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PDE4D Antibody (OAGA00330)"?
This target may also be called "DPDE3, PDE43, STRK1, ACRDYS2, HSPDE4D, PDE4DN2" in publications.
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What is the shipping cost for "PDE4D Antibody (OAGA00330)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PDE4D Antibody (OAGA00330)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PDE4D Antibody (OAGA00330)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "91 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PDE4D Antibody (OAGA00330)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "PDE4D"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "PDE4D"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "PDE4D"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "PDE4D"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "PDE4D"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "PDE4D"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.