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Catalog No: AVARP09045_P050
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AVARP09045_P050
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Datasheets/ManualsPrintable datasheet for anti-PDCD4 (AVARP09045_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human PDCD4
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: MTKYPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSINEARINAKAKR
Concentration0.5 mg/ml
Blocking PeptideFor anti-PDCD4 (AVARP09045_P050) antibody is Catalog # AAP30594 (Previous Catalog # AAPP01246)
ReferenceYang,H.S., et al., (2004) Mol. Cell. Biol. 24 (9), 3894-3906
Publications

Folini, M. et al. miR-21: an oncomir on strike in prostate cancer. Mol. Cancer 9, 12 (2010). 20092645

Pan, Q., Luo, X. & Chegini, N. microRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cells. Mol. Hum. Reprod. 16, 215-27 (2010). 19906824

Gene SymbolPDCD4
Gene Full NameProgrammed cell death 4 (neoplastic transformation inhibitor)
Alias SymbolsH731
NCBI Gene Id27250
Protein NameProgrammed cell death protein 4
Description of TargetPDCD4 is a protein localized to the nucleus in proliferating cells. Expression of its gene is modulated by cytokines in natural killer and T cells. PDCD4 is thought to play a role in apoptosis but the specific role has not yet been determined.This gene encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified.
Uniprot IDQ53EL6
Protein Accession #NP_663314
Nucleotide Accession #NM_145341
Protein Size (# AA)458
Molecular Weight50kDa
Protein InteractionsEIF4A2; FBXW11; EIF4A3; PAIP1; ARPC1B; UFD1L; TPD52; BTF3; AAMP; IGSF8; CD81; DAXX; UBC; CSNK2A1; VCP; NR1H2; PSEN2; PSEN1; NAP1L1; APOE; BTRC; RPS6KA1; EIF4A1; ELAVL1; SUMO2; EMD; PDCD4; EIF4G1; RPL5; RPLP1; RPS13;
  1. What is the species homology for "PDCD4 Antibody - N-terminal region (AVARP09045_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Rabbit".

  2. How long will it take to receive "PDCD4 Antibody - N-terminal region (AVARP09045_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "PDCD4 Antibody - N-terminal region (AVARP09045_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "PDCD4 Antibody - N-terminal region (AVARP09045_P050)"?

    This target may also be called "H731" in publications.

  5. What is the shipping cost for "PDCD4 Antibody - N-terminal region (AVARP09045_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "PDCD4 Antibody - N-terminal region (AVARP09045_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "PDCD4 Antibody - N-terminal region (AVARP09045_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "50kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "PDCD4 Antibody - N-terminal region (AVARP09045_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "PDCD4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "PDCD4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "PDCD4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "PDCD4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "PDCD4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "PDCD4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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