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| Datasheets/Manuals | Printable datasheet for PAX8 Antibody - N-terminal region (OAEB02411) |
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| Predicted Species Reactivity | Human|Mouse|Rat |
|---|---|
| Product Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
| Clonality | Polyclonal |
| Host | Goat |
| Application | WB, IHC |
| Reconstitution and Storage | Aliquot and store at -20C. Minimize freezing and thawing. |
| Immunogen | PAX8 |
| Purification | Ammonium Sulfate Precipitated; Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100% |
| Peptide Sequence | PHNSIRSGHGGLN-C |
| Concentration | 0.5 mg/ml |
| Purity | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Application Info | Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Approx 40kDa band observed in Human Liver lysates (calculated MW of xxkDa according to NP_039245.1). Recommended concentration: 1-3ug/ml. Immunohistochemistry: In paraffin embedded Human Thyroid Gland shows nuclear staining in epithelial cells around follicles. Recommended concentration, 1-2ug/ml. A customer found this antibody unsuccessful in immunohistochemistry on Mouse tissues. |
| Reference | * Borgogni E, Sarchielli E, Sottili M, Santarlasci V, Cosmi L, Gelmini S, Lombardi A, Cantini G, Perigli G, Luconi M, Vannelli GB, Annunziato F, Adorini L, Serio M, Crescioli C.; Elocalcitol inhibits inflammatory responses in human thyroid cells and T cells.; Endocrinology. 2008 Jul;149(7):3626-34.; Pubmed 18372324 * Crescioli C, Cosmi L, Borgogni E, Santarlasci V, Gelmini S, Sottili M, Sarchielli E, Mazzinghi B, Francalanci M, Pezzatini A, Perigli G, Vannelli GB, Annunziato F, Serio M.; Methimazole inhibits CXC chemokine ligand 10 secretion in human thyrocytes.; J Endocrinol. 2007 Oct;195(1):145-55.; Pubmed 17911406 * Pasca di Magliano M, Di Lauro R, Zannini M.; Pax8 has a key role in thyroid cell differentiation.; Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13144-9.; Pubmed 11069301 |
| Gene Symbol | Pax8|PAX8 |
|---|---|
| Gene Full Name | paired box 8 |
| Alias Symbols | paired box gene 8;paired box protein Pax-8;paired domain gene 8;Pax;Pax-8;Pax-8 protein. |
| NCBI Gene Id | 18510|7849|81819 |
| Protein Name | Paired box protein Pax-8 |
| Uniprot ID | Q06710 |
| Protein Accession # | NP_003457.1 |
| Molecular Weight | 48.2; 41.7; 43.0; 34.9; 31.0 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "PAX8 Antibody - N-terminal region (OAEB02411)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "PAX8 Antibody - N-terminal region (OAEB02411)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "PAX8 Antibody - N-terminal region (OAEB02411)" provided in?
This item is provided in "Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "PAX8 Antibody - N-terminal region (OAEB02411)"?
This target may also be called "paired box gene 8;paired box protein Pax-8;paired domain gene 8;Pax;Pax-8;Pax-8 protein." in publications.
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What is the shipping cost for "PAX8 Antibody - N-terminal region (OAEB02411)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "PAX8 Antibody - N-terminal region (OAEB02411)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "PAX8 Antibody - N-terminal region (OAEB02411)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "48.2; 41.7; 43.0; 34.9; 31.0".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "PAX8 Antibody - N-terminal region (OAEB02411)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "Pax8|PAX8"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "Pax8|PAX8"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "Pax8|PAX8"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "Pax8|PAX8"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "Pax8|PAX8"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "Pax8|PAX8"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
