Catalog No: ARP35518_T100
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ARP35518_T100
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Datasheets/ManualsPrintable datasheet for anti-P2RX7 (ARP35518_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human P2RX7
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 79%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%
Peptide SequenceSynthetic peptide located within the following region: IQSMNYGTIKWFFHVIIFSYVCFALVSDKLYQRKEPVISSVHTKVKGIAE
Concentration1.0 mg/ml
Blocking PeptideFor anti-P2RX7 (ARP35518_T100) antibody is Catalog # AAP35518 (Previous Catalog # AAPP06758)
ReferenceBuell,GN., et al., (1998) Receptors Channels 5(6):347-54
Publications

Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells. Mol. Cancer. 14, 201 (2015). 26597723

Gene SymbolP2RX7
Gene Full NamePurinergic receptor P2X, ligand-gated ion channel, 7
Alias SymbolsP2X7
NCBI Gene Id5027
Protein NameP2X purinoceptor 7
Description of TargetThe product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
Uniprot IDQ99572
Protein Size (# AA)595
Molecular Weight69kDa
Protein InteractionsKRTAP10-8; KRT31; TM9SF1; CASK; EFNB3; EMP3; PANX1; SVIL; ACTB;
  1. What is the species homology for "P2RX7 Antibody - N-terminal region (ARP35518_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "P2RX7 Antibody - N-terminal region (ARP35518_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "P2RX7 Antibody - N-terminal region (ARP35518_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "P2RX7 Antibody - N-terminal region (ARP35518_T100)"?

    This target may also be called "P2X7" in publications.

  5. What is the shipping cost for "P2RX7 Antibody - N-terminal region (ARP35518_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "P2RX7 Antibody - N-terminal region (ARP35518_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "P2RX7 Antibody - N-terminal region (ARP35518_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "69kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "P2RX7 Antibody - N-terminal region (ARP35518_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "P2RX7"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "P2RX7"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "P2RX7"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "P2RX7"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "P2RX7"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "P2RX7"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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