Catalog No: ARP38669_T100
Price: $0.00
SKU
ARP38669_T100
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Datasheets/ManualsPrintable datasheet for anti-NR1H3 (ARP38669_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Cow, Dog, Goat, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human NR1H3
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 85%; Dog: 79%; Goat: 85%; Horse: 79%; Human: 100%; Pig: 77%; Rabbit: 86%
Peptide SequenceSynthetic peptide located within the following region: MSLWLGAPVPDIPPDSAVELWKPGAQDASSQAQGGSSCILREEARMPHSA
Concentration1.0 mg/ml
Blocking PeptideFor anti-NR1H3 (ARP38669_T100) antibody is Catalog # AAP38669 (Previous Catalog # AAPP20858)
ReferenceAlbers,M., et al., (2006) J. Biol. Chem. 281 (8), 4920-4930
Gene SymbolNR1H3
Gene Full NameNuclear receptor subfamily 1, group H, member 3
Alias SymbolsLXRA, LXR-a, RLD-1
NCBI Gene Id10062
Protein NameOxysterols receptor LXR-alpha
Description of TargetInteraction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis.
Uniprot IDQ13133
Protein Accession #NP_005684
Nucleotide Accession #NM_005693
Protein Size (# AA)447
Molecular Weight50kDa
Protein InteractionsRXRG; RXRB; MDFI; SUV39H1; KDM1A; BARD1; MSTO1; HSP90AA1; PIAS1; APP; NR3C1; MYC; ZXDC; TMEM161A; ING3; NCOA6; NCOR1; KAT2B; EIF3I; NRIP1; NCOA3; SRC; RXRA; FOXO3; ACTN1; SS18L1; LZTR1; EDF1; RARA; NR0B2; SYT1; PPARA; SIRT1; UBC; CEP350;
  1. What is the species homology for "NR1H3 Antibody - N-terminal region (ARP38669_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Cow, Dog, Goat, Horse, Pig, Rabbit".

  2. How long will it take to receive "NR1H3 Antibody - N-terminal region (ARP38669_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "NR1H3 Antibody - N-terminal region (ARP38669_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NR1H3 Antibody - N-terminal region (ARP38669_T100)"?

    This target may also be called "LXRA, LXR-a, RLD-1" in publications.

  5. What is the shipping cost for "NR1H3 Antibody - N-terminal region (ARP38669_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NR1H3 Antibody - N-terminal region (ARP38669_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NR1H3 Antibody - N-terminal region (ARP38669_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "50kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NR1H3 Antibody - N-terminal region (ARP38669_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NR1H3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NR1H3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NR1H3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NR1H3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NR1H3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NR1H3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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