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Catalog No: OACA07708
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OACA07708
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for NKX2-5 Antibody (OACA07708) (OACA07708)
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunohistochemistry
Reconstitution and Storage-20°C or -80°C
ImmunogenRecombinant Human Homeobox protein Nkx-2.5 protein (1-135AA)
PurificationAffinity Purified
Preservative0.02% sodium azide
FormulationPBS with, 50% glycerol, pH7.3.
Reference[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36:40-45(2004). [2]"The DNA sequence and comparative analysis of human chromosome 5." Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S. Rubin E.M.Nature 431:268-274(2004). [3]"Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module."Koss M., Bolze A., Brendolan A., Saggese M., Capellini T.D., Bojilova E., Boisson B., Prall O.W., Elliott D.A., Solloway M., Lenti E., Hidaka C., Chang C.P., Mahlaoui N., Harvey R.P., Casanova J.L., Selleri L.Dev. Cell 22:913-926(2012).
Gene SymbolNKX2-5
Gene Full NameNK2 homeobox 5
Alias SymbolsCardiac-specific homeobox;cardiac-specific homeobox 1;CHNG5;CSX;CSX1;HLHS2;homeobox protein CSX;homeobox protein NK-2 homolog E;homeobox protein NKX 2-5;homeobox protein Nkx-2.5;NK2 transcription factor related, locus 5;NKX 2-5;NKX2.5;NKX2E;NKX4-1;tinman homolog;tinman paralog;VSD3.
NCBI Gene Id1482
Protein NameHomeobox protein Nkx-2.5
Description of TargetImplicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). Binds to the core DNA motif of NPPA promoter (PubMed:22849347, PubMed:26926761). It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity). It is required for spleen development.
Uniprot IDP52952
Protein Accession #NP_001159647
Nucleotide Accession #NM_001166175
  1. What is the species homology for "NKX2-5 Antibody (OACA07708)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "NKX2-5 Antibody (OACA07708)"?

    This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".

  3. What buffer format is "NKX2-5 Antibody (OACA07708)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "NKX2-5 Antibody (OACA07708)"?

    This target may also be called "Cardiac-specific homeobox;cardiac-specific homeobox 1;CHNG5;CSX;CSX1;HLHS2;homeobox protein CSX;homeobox protein NK-2 homolog E;homeobox protein NKX 2-5;homeobox protein Nkx-2.5;NK2 transcription factor related, locus 5;NKX 2-5;NKX2.5;NKX2E;NKX4-1;tinman homolog;tinman paralog;VSD3." in publications.

  5. What is the shipping cost for "NKX2-5 Antibody (OACA07708)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "NKX2-5 Antibody (OACA07708)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "NKX2-5 Antibody (OACA07708)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "NKX2-5 Antibody (OACA07708)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "NKX2-5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "NKX2-5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "NKX2-5"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "NKX2-5"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "NKX2-5"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "NKX2-5"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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