NFKBIA Antibody (Phospho-Ser32/36) (OASG03750)

Catalog No: OASG03750

Size:100 uL

Western Blot using COS7

Western Blot

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Monkey
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC, IF
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human IKappaB- Alpha around the phosphorylation site of S32/S36. Location: 10-90aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Ser32/36
• Specificity: Phospho-IKappaB- Alpha (S32/S36) Polyclonal Antibody detects endogenous levels of IKappaB- Alpha protein only when phosphorylated at S32/S36.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000;

Target Info

• Gene Symbol: NFKBIA
• Gene Full Name: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
• Alias Symbols: IKBA, MAD-3, NFKBI, EDAID2
• NCBI Gene Id: 4792; 18035; 25493
• Description of Target: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
• Uniprot ID: P25963, Q9Z1E3, Q63746
• Molecular Weight: 36 kDa