NFATC1 Antibody (OAPA00289)

Catalog No: OAPA00289 (Formerly GWB-BSP930)

Size:5UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
• Clonality: Monoclonal
• Clone: PAT1C3AT.
• Isotype: Mouse IgG2a heavy chain and kappa light chain.
• Host: Mouse
• Application: WB
  Product Type: Mouse Anti Human Monoclonal.
  Product Introduction: NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least 2 components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play an essential role in inducible gene transcription during immune response. NFATC1 is an inducible nuclear component. NFATC1 functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of NFATC1 may regulate inducible expression of different cytokine genes.
• Reconstitution and Storage: For periods up to 1 month store at 4C, for longer periods of time, store at -20C. Prevent freeze thaw cycles.
  Stability: 12 months at -20C. 1 month at 4C.
• Immunogen: The immunogen for anti-NFATC1 antibody: anti-human NFATC1 mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human NFATC1 amino acids 428-716 purified from E. coli.
• Purity: NFATC1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
• Application Info: NFATC1 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000.

Target Info

• Gene Symbol: NFATC1
• Alias Symbols: NFAT2, NFATc, NF-ATC, NF-ATc1.2
• NCBI Gene Id: 4772
• Protein Name: Nuclear factor of activated T-cells c1 isoform IB-IXL
• Description of Target: Mouse Anti Human Nuclear factor of activated T-cells cytoplasmic 1
• Uniprot ID: B5B2M5