MVP Antibody (OAGA01032)

Catalog No: OAGA01032

Size:100 ul

Sample (30 ug of whole cell lysate)
A: Molt-4
7.5% SDS PAGE
OAGA01032 diluted at 1:1000

MVP/LRP antibody detects MVP protein by Western blot analysis.
A. 30 ug Neuro2A whole cell lysate/extract
B. 30 ug GL261 whole cell lysate/extract
C. 30 ug C8D30 whole cell lysate/extract
D. 30 ug BCL-1 whole cell lysate/extract
E. 30 ug Raw264.7 whole cell lysate/extract
7.5 % SDS-PAGE
MVP/LRP antibody (OAGA01032) dilution: 1:1000

Immunohistochemical analysis of paraffin-embedded A549 xenograft, using LRP(MVP)(OAGA01032) antibody at 1:500 dilution.

Immunofluorescence analysis of paraformaldehyde-fixed A431, using MVP/LRP(OAGA01032) antibody at 1:200 dilution.

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH 7) with 0.01% Thimerosal added as a preservative
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: ICC, IF, IHC-FFPE, WB
• Reconstitution and Storage: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human MVP/LRP. The exact sequence is proprietary.
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Application Info: ICC/IF: 1:100~1000
  IHC-P: 1:100~1000
  WB: 1:500~3000
• Publications:

  Major Vault Protein, a Candidate Gene in 16p11.2 Microdeletion Syndrome, Is Required for the Homeostatic Regulation of Visual Cortical Plasticity. J Neurosci. 38, 3890-3900 (2018). 29540554

• Description:
  View product citations for MVP Antibody (OAGA01032) on CiteAb

Target Info

• Gene Symbol: MVP
• Gene Full Name: Major vault protein
• Alias Symbols: LRP, VAULT1
• NCBI Gene Id: 9961
• Protein Name: Major vault protein
• Description of Target: This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
• Uniprot ID: Q14764
• Protein Accession #: NP_005106.2
• Molecular Weight: 99 kDa