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MTNR1B Antibody - N-terminal region (ARP64072_P050)
Datasheets/Manuals | Printable datasheet for anti-MTNR1B (ARP64072_P050) antibody |
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Tested Species Reactivity | Human | ||||||
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Predicted Species Reactivity | Human, Pig, Rabbit | ||||||
Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. | ||||||
Clonality | Polyclonal | ||||||
Host | Rabbit | ||||||
Application | WB | ||||||
Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. | ||||||
Purification | Affinity Purified | ||||||
Predicted Homology Based on Immunogen Sequence | Human: 100%; Pig: 79%; Rabbit: 79% | ||||||
Peptide Sequence | Synthetic peptide located within the following region: SFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDV | ||||||
Concentration | 0.5 mg/ml | ||||||
Blocking Peptide | For anti-MTNR1B (ARP64072_P050) antibody is Catalog # AAP64072 | ||||||
Enhanced Validation |
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Publications | Melatonin enhances porcine embryo development via the Nrf2/ARE signaling pathway. J Mol Endocrinol. 63, 175-185 (2019). 31408847 Melatonin-Nrf2 Signaling Activates Peroxisomal Activities in Porcine Cumulus Cell-Oocyte Complexes. Antioxidants (Basel). 9, (2020). 33153240 Santoro, R. et al. Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation. Carcinogenesis 34, 1051-61 (2013). 23354312 Stimulatory Effects of Melatonin on Porcine In Vitro Maturation Are Mediated by MT2 Receptor. Int J Mol Sci. 19, (2018). 29861447 | ||||||
Description |
Gene Symbol | MTNR1B |
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Gene Full Name | Melatonin receptor 1B |
Alias Symbols | MT2, FGQTL2, MEL-1B-R |
NCBI Gene Id | 4544 |
Protein Name | Melatonin receptor type 1B |
Description of Target | This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. |
Uniprot ID | P49286 |
Protein Accession # | NP_005950 |
Nucleotide Accession # | NM_005959 |
Protein Size (# AA) | 362 |
Molecular Weight | 40 kDa |
Protein Interactions | GNAI1; GPR50; ITM2C; HNRNPA0; GNB4; PPM1G; PI4KA; PDIA6; VPS35; IRS4; COPA; CTNND1; MTNR1B; MTNR1A; FLNA; YWHAQ; GNB1; GNAI3; GNAI2; HSPA5; CANX; |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Pig, Rabbit".
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How long will it take to receive "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "MTNR1B Antibody - N-terminal region (ARP64072_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?
This target may also be called "MT2, FGQTL2, MEL-1B-R" in publications.
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What is the shipping cost for "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "40 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "MTNR1B Antibody - N-terminal region (ARP64072_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "MTNR1B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "MTNR1B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "MTNR1B"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "MTNR1B"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "MTNR1B"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "MTNR1B"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.