Catalog No: OAPA00114 (Formerly GWB-27B84D)
Size:500UG
Price: $334.00
SKU
OAPA00114
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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MHC Class II Antibody (OAPA00114)

Datasheets/ManualsPrintable datasheet for anti-MHC Class II antibody - OAPA00114
Product Info
Product FormatLyophilized
ClonalityMonoclonal
CloneNYRmI-A.
IsotypeMouse IgG2a.
HostMouse
Additional InformationAntibody Properties: Cytotoxic and staining antibody. For staining, use 10 ml/106 cells. Titer for cytotoxicity should be determined by the investigator.
::Product Introduction: MHC Class II is consists of 2 membrane spanning proteins. Each of these proteins is roughly 30 kDa, and has of two Globular domains, Alpha-1, Alpha-2, Beta-1 and Beta-2. The two regions farthest away from the membrane are alpha-1 and beta-1. The two proteins link without Covalent Bonds. The MHC Class II protein mainly presents peptides, which have been digested from external sources. MHC Class II is normally only expressed by Antigen Presenting Cells (APC) which digest foreign protein. Within the RER the alpha and beta proteins of the molecule, associate with each other, while a third protein called the "invariant chain," is necessary for stabilizing the complex, without it, they will not associate. The MHC-invariant complex is then passed from the RER, into and out of, the Golgi body. It fuses with an Endocytic compartment, where an external protein has been sampled and degraded.
Reconstitution and StorageReconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Storage: Lyophilized: store at 4C. After reconstitution, if not intended for use within a month, aliquot and store at -20C.
ImmunogenThe immunogen for anti-MHC Class II antibody: purified mouse LN B cells (C3H anti-C57Bl6).
PurificationIon exchange column.
Concentration1mg/ml in PBS (after reconstitution)
SpecificityRecognizes most MHC class II haplotypes (b,f,p,q,r,s,u,v), but weak against I-Ak.
Gene SymbolMHC Class II
Alias SymbolsIDDM1, CELIAC1, HLA-DQB
NCBI Gene Id3119
Protein NameMHC class II HLA-DQ-beta-1 EMBL AAC41965.1
Description of TargetMouse Anti MHC Class II (I-A)
Uniprot IDO19707
  1. What is the species homology for "MHC Class II Antibody (OAPA00114)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "".

  2. How long will it take to receive "MHC Class II Antibody (OAPA00114)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "MHC Class II Antibody (OAPA00114)" provided in?

    This item is provided in "Lyophilized".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MHC Class II Antibody (OAPA00114)"?

    This target may also be called "IDDM1, CELIAC1, HLA-DQB" in publications.

  5. What is the shipping cost for "MHC Class II Antibody (OAPA00114)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MHC Class II Antibody (OAPA00114)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MHC Class II Antibody (OAPA00114)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MHC Class II Antibody (OAPA00114)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MHC CLASS II"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MHC CLASS II"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MHC CLASS II"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MHC CLASS II"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MHC CLASS II"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MHC CLASS II"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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