MESP1 Antibody - N-terminal region (ARP39374_P050)

Catalog No: ARP39374_P050

WB Suggested Anti-MESP1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: 293T cell lysate

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Dog
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MESP1
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Dog: 85%; Human: 100%
• Peptide Sequence: Synthetic peptide located within the following region: SLVSSPDSWGSTPADSPVASPARPGTLRDPRAPSVGRRGARSSRLGSGQR
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-MESP1 (ARP39374_P050) antibody is Catalog # AAP39374 (Previous Catalog # AAPP21385)
• Reference: David,R., (2008) Nat. Cell Biol. 10 (3), 338-345
• Publications:

  Cao, N. et al. Highly efficient induction and long-term maintenance of multipotent cardiovascular progenitors from human pluripotent stem cells under defined conditions. Cell Res. 23, 1119-32 (2013). 23896987

  Generation of Clinical-grade Functional Cardiomyocytes from Human Embryonic Stem Cells in Chemically Defined Conditions. J Tissue Eng Regen Med. , (2016). 27943600

  Homozygous MESP1 knock-in reporter hESCs facilitated cardiovascular cell differentiation and myocardial infarction repair. Theranostics. 10, 6898-6914 (2020). 32550911

  Patient-specific cardiovascular progenitor cells derived from integration-free induced pluripotent stem cells for vascular tissue regeneration. Biomaterials. 73, 51-9 (2015). 26398309

  SWI/SNF Component BAF250a Coordinates OCT4 and WNT Signaling Pathway to Control Cardiac Lineage Differentiation. Front Cell Dev Biol. 7, 358 (2020). 32039194

  Tennis, M. A. et al. Prostacyclin inhibits non-small cell lung cancer growth by a frizzled 9-dependent pathway that is blocked by secreted frizzled-related protein 1. Neoplasia 12, 244-53 (2010). 20335662

• Description:
  View product citations for MESP1 Antibody - N-terminal region (ARP39374_P050) on CiteAb

Target Info

• Gene Symbol: MESP1
• Gene Full Name: Mesoderm posterior 1 homolog (mouse)
• Alias Symbols: bHLHc5
• NCBI Gene Id: 55897
• Protein Name: Mesoderm posterior protein 1
• Description of Target: MESP1 is a transcription factor. MESP1 plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. MESP1 defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.
• Uniprot ID: Q9BRJ9
• Protein Accession #: NP_061140
• Nucleotide Accession #: NM_018670
• Protein Size (# AA): 268
• Molecular Weight: 28kDa