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Catalog No: ARP34223_P050
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ARP34223_P050
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Datasheets/ManualsPrintable datasheet for anti-MEF2A (ARP34223_P050) antibody
Product Info
Tested Species ReactivityRat
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human MEF2A
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Peptide SequenceSynthetic peptide located within the following region: YNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINEE
Concentration0.5 mg/ml
Blocking PeptideFor anti-MEF2A (ARP34223_P050) antibody is Catalog # AAP34223 (Previous Catalog # AAPP05538)
ReferenceRamachandran,B., (2008) J. Biol. Chem. 283 (18), 11935-11946
Gene SymbolMEF2A
Gene Full NameMyocyte enhancer factor 2A
Alias Symbolsmef2, ADCAD1, RSRFC4, RSRFC9
NCBI Gene Id4205
Protein NameMyocyte-specific enhancer factor 2A
Description of TargetThe process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD, myogenin, MYF5, and MRF4 are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes.The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDQ02078
Protein Accession #NP_005578
Nucleotide Accession #NM_005587
Protein Size (# AA)507
Molecular Weight55kDa
Protein InteractionsHDAC7; HDAC5; HDAC3; TAF8; GNG12; TBP; GNB2; ERBB2IP; NDUFB9; DDB1; Dlg4; PHB2; ASCL1; SUMO1; UBE2I; SUMO2; HNRNPA1; UBC; MEF2D; HDAC1; EP300; HDAC4; ACTN4; THRA; HDAC9; MAPK7; CASP7; SMAD2; SMAD4; MEF2A; CASP3; MAPK14; TEAD1; MYOG; MYOD1; CDK5; VGLL4;
  1. What is the species homology for "MEF2A Antibody - N-terminal region (ARP34223_P050)"?

    The tested species reactivity for this item is "Rat". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish".

  2. How long will it take to receive "MEF2A Antibody - N-terminal region (ARP34223_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "MEF2A Antibody - N-terminal region (ARP34223_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MEF2A Antibody - N-terminal region (ARP34223_P050)"?

    This target may also be called "mef2, ADCAD1, RSRFC4, RSRFC9" in publications.

  5. What is the shipping cost for "MEF2A Antibody - N-terminal region (ARP34223_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MEF2A Antibody - N-terminal region (ARP34223_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MEF2A Antibody - N-terminal region (ARP34223_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "55kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MEF2A Antibody - N-terminal region (ARP34223_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MEF2A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MEF2A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MEF2A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MEF2A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MEF2A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MEF2A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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