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Catalog No: ARP32794_P050
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ARP32794_P050
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Datasheets/ManualsPrintable datasheet for anti-ME1 (ARP32794_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human ME1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 92%; Dog: 85%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 91%; Rabbit: 100%; Rat: 100%; Sheep: 92%
Peptide SequenceSynthetic peptide located within the following region: QQLNIHGLLPPSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKL
Concentration0.5 mg/ml
Blocking PeptideFor anti-ME1 (ARP32794_P050) antibody is Catalog # AAP32794 (Previous Catalog # AAPP03813)
Sample Type Confirmation

ME1 is strongly supported by BioGPS gene expression data to be expressed in HEK293T

ReferenceHsieh,J.Y., (2006) J. Biol. Chem. 281 (32), 23237-23245
Gene SymbolME1
Gene Full NameMalic enzyme 1, NADP(+)-dependent, cytosolic
Alias SymbolsMES, HUMNDME
NCBI Gene Id4199
Protein NameNADP-dependent malic enzyme
Description of TargetME1 is a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDP48163
Protein Accession #NP_002386
Nucleotide Accession #NM_002395
Protein Size (# AA)572
Molecular Weight64kDa
Protein InteractionsUBC; VTA1; RPUSD2; GORASP2; BOP1; TOM1; NMI; CUL3; UGDH; TBCD; GTF2A1; GARS; CTTN;
  1. What is the species homology for "ME1 Antibody - N-terminal region (ARP32794_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep".

  2. How long will it take to receive "ME1 Antibody - N-terminal region (ARP32794_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "ME1 Antibody - N-terminal region (ARP32794_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ME1 Antibody - N-terminal region (ARP32794_P050)"?

    This target may also be called "MES, HUMNDME" in publications.

  5. What is the shipping cost for "ME1 Antibody - N-terminal region (ARP32794_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ME1 Antibody - N-terminal region (ARP32794_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ME1 Antibody - N-terminal region (ARP32794_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "64kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ME1 Antibody - N-terminal region (ARP32794_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ME1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ME1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ME1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ME1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ME1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ME1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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