MAPK8IP2 Antibody (OAAF02406)

Catalog No: OAAF02406 (Formerly GWB-ASD641)

Size:100 ug

Western blot analysis of extracts from mouse brain cells, using JIP2 Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using JIP2 Antibody. The picture on the right is treated with the synthesized peptide.

Immunofluorescence analysis of HeLa cells, using JIP2 Antibody. The picture on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
• Reconstitution and Storage: -20°C
• Immunogen: The antiserum was produced against synthesized peptide derived from human JIP2.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Specificity: JIP2 antibody detects endogenous levels of total JIP2 protein.
• Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Dilution: The optimal working dilution should be determined by the end user.
• Application Info: WB: 1:500~1:3000; IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:5000
• Reference: Yasuda J., Mol. Cell. Biol. 19:7245-7254(1999).
  Negri S., Genomics 64:324-330(2000).
  Dunham I., Nature 402:489-495(1999).

Target Info

• Gene Symbol: MAPK8IP2
• Gene Full Name: mitogen-activated protein kinase 8 interacting protein 2
• Alias Symbols: C-Jun-amino-terminal kinase-interacting protein 2;homologous to mouse JIP-1;IB2;IB-2;islet-brain 2;Islet-brain-2;JIP2;JNK MAP kinase scaffold protein 2;JNK MAP kinase scaffold protein JIP2;JNK-interacting protein 2;Mitogen-activated protein kinase 8-interacting protein 2;PRKM8IPL.
• NCBI Gene Id: 23542
• Protein Name: C-Jun-amino-terminal kinase-interacting protein 2
• Description of Target: The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity).
• Uniprot ID: Q13387
• Protein Accession #: NP_036456.1
• Molecular Weight: 87 kDa