Catalog No: OAPA00351 (Formerly GWB-BSP847)
Size:5UG
Price: $75.00
SKU
OAPA00351
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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MAPK3 Antibody (OAPA00351)

Datasheets/ManualsPrintable datasheet for anti-MAPK3 antibody - OAPA00351
Product Info
Predicted Species ReactivityHuman
Product Format1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
ClonalityMonoclonal
ClonePAT1A2AT
IsotypeMouse IgG2b heavy chain and kappa light chain.
HostMouse
ApplicationIF, WB
::Product Introduction: Extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinaseintracellular signalingmolecules which are involved in functions including the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virusinfection, ligands for heterotrimeric G protein-coupled receptors, transforming agents, and carcinogens, activate the ERK pathway. The term, "extracellular signal-regulated kinases", is sometimes used as a synonym for mitogen-activated protein kinase(MAPK), but has more recently been adopted for a specific subset of the mammalianMAPK family. In the MAPK/ERK pathway, Rasactivates c-Raf, followed by MEKand then MAPK1/2 (below). Ras is typically activated by growth hormones through receptor tyrosine kinasesand GRB2/SOS, but may also receive other signals. ERKs are known to activate many transcription factors and some downstream protein kinases. Disruption of th
Reconstitution and StorageFor periods up to 1 month store at 4C, for longer periods of time, store at -20C. Prevent freeze thaw cycles.
Stability: 12 months at -20C. 1 month at 4C.
ImmunogenThe immunogen for anti-MAPK3 antibody: anti-human MAPK3 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human MAPK3 amino acids 1-137 purified from E. coli.
Predicted Homology Based on Immunogen SequenceHuman
PurityMAPK3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Application InfoMAPK3 antibody has been tested by ELISA, Western blot, and Immunofluorescence to assure specificity and reactivity. Since applications vary, however, each investigation should be titrated by a reagent to obtain optimal results. Recommended dilution range for Western blot analysis and Immunofluorescence is 1:250 ~ 500. Recommended starting dilution is 1:500.
Gene SymbolMAPK3
Alias SymbolsERK1, ERT2, ERK-1, PRKM3, P44ERK1, P44MAPK, HS44KDAP, HUMKER1A, p44-ERK1, p44-MAPK
NCBI Gene Id5595
Protein NameMitogen-activated protein kinase 3
Description of TargetMouse Anti Human Mitogen-Activated Protein Kinase 3
Uniprot IDP27361
  1. What is the species homology for "MAPK3 Antibody (OAPA00351)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "MAPK3 Antibody (OAPA00351)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "MAPK3 Antibody (OAPA00351)" provided in?

    This item is provided in "1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "MAPK3 Antibody (OAPA00351)"?

    This target may also be called "ERK1, ERT2, ERK-1, PRKM3, P44ERK1, P44MAPK, HS44KDAP, HUMKER1A, p44-ERK1, p44-MAPK" in publications.

  5. What is the shipping cost for "MAPK3 Antibody (OAPA00351)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "MAPK3 Antibody (OAPA00351)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "MAPK3 Antibody (OAPA00351)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "MAPK3 Antibody (OAPA00351)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "MAPK3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "MAPK3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "MAPK3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "MAPK3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "MAPK3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "MAPK3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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