MAP1LC3A Antibody - N-terminal region (ARP51335_P050)

Catalog No: ARP51335_P050

WB Suggested Anti-MAP1LC3A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human brain

Rabbit Anti-MAP1LC3A Antibody
Catalog Number: ARP51335_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Cytoplasmic
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP1LC3A
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 86%
• Peptide Sequence: Synthetic peptide located within the following region: MKMRFFSSPCGKAAVDPADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPV
• Concentration: 0.5 mg/ml
• Blocking Peptide: Catalog # AAP51335 (Previous Catalog # AAPS23512)
• Reference: Taylor,M.P. (2007) J. Virol. 81 (22), 12543-12553
• Publications:

  Icariside II, a phosphodiesterase 5 inhibitor, attenuates cerebral ischaemia/reperfusion injury by inhibiting glycogen synthase kinase-3β-mediated activation of autophagy. Br J Pharmacol. 177, 1434-1452 (2020). 31658364

• Description:
  View product citations for MAP1LC3A Antibody - N-terminal region (ARP51335_P050) on CiteAb

Target Info

• Gene Symbol: MAP1LC3A
• Gene Full Name: Microtubule-associated protein 1 light chain 3 alpha
• Alias Symbols: LC3, LC3A, ATG8E, MAP1ALC3, MAP1BLC3
• NCBI Gene Id: 84557
• Protein Name: Microtubule-associated proteins 1A/1B light chain 3A
• Description of Target: MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3A is one of the light chain subunits and can associate with either MAP1A or MAP1B.MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: Q9H492-2
• Protein Accession #: NP_852610
• Nucleotide Accession #: NM_181509
• Protein Size (# AA): 125
• Molecular Weight: 14kDa
• Protein Interactions: FAM134C; FUNDC1; KXD1; tat; TNIP1; SQSTM1; UBC; OPTN; TOLLIP; EPAS1; ATG4B; LGALS3; ATG13; ATG101; SRPK1; HNRNPM; PGAP1; FYCO1; UBQLN4; PADI3; UBQLN1; PELP1; SERBP1; DDX17; TUBB4B; TUBA1B; MATR3; VPRBP; ASAP2; CLTCL1; HNRNPU; HNRNPH1; EPRS; EPHA7; EGFR; D