LYPD1 Antibody - C-terminal region (OAAB06345)

Catalog No: OAAB06345 (Formerly GWB-P6FEGP)

Size:400ul

Western blot analysis of LYPD1 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane). LYPD1 (arrow) was detected using the purified Pab.

LYPD1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LYPD1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Host: Rabbit
• Application: WB, IHC, ELISA
• Additional Information: Cellular Location: Cell membrane; Lipid-anchor, GPI-anchor
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This LYPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the C-terminal region of human LYPD1.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: 0.5 mg/ml
• Application Info: WB: 1:1000
  IHC-P: 1:50~100

Target Info

• Gene Symbol: LYPD1
• Alias Symbols: PHTS, LYPDC1
• NCBI Gene Id: 116372
• Protein Name: Ly6/PLAUR domain-containing protein 1
• Description of Target: Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha- 4:beta-2-containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety.
• Uniprot ID: Q8N2G4
• Protein Accession #: NP_001070895.1
• Molecular Weight: 15 kDa