Catalog No: ARP44723_P050
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ARP44723_P050
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Datasheets/ManualsPrintable datasheet for anti-LRP8 (ARP44723_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Additional InformationIHC Information: Paraffin embedded brain, cortex tissue, tested with an antibody dilution of 5 ug/ml.
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human LRP8
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 85%
Peptide SequenceSynthetic peptide located within the following region: ATVDGGRRRTLFSRNLSEPRAIAVDPLRGFMYWSDWGDQAKIEKSGLNGV
Concentration0.5 mg/ml
Blocking PeptideFor anti-LRP8 (ARP44723_P050) antibody is Catalog # AAP44723 (Previous Catalog # AAPP12195)
ReferenceHoe,H.S., (2008) J. Biol. Chem. 283 (10), 6288-6299
Gene SymbolLRP8
Gene Full NameLow density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Alias SymbolsMCI1, LRP-8, APOER2, HSZ75190
NCBI Gene Id7804
Protein NameLow-density lipoprotein receptor-related protein 8
Description of TargetLRP8 is an apolipoprotein E receptor, a member of the low density lipoprotein receptor (LDLR) family. Apolipoprotein E is a small lipophilic plasma protein and a component of lipoproteins such as chylomicron remnants, very low density lipoprotein (VLDL), and high density lipoprotein (HDL). The apolipoprotein E receptor is involved in cellular recognition and internalization of these lipoproteins.This gene encodes an apolipoprotein E receptor, a member of the low density lipoprotein receptor (LDLR) family. Apolipoprotein E is a small lipophilic plasma protein and a component of lipoproteins such as chylomicron remnants, very low density lipoprotein (VLDL), and high density lipoprotein (HDL). The apolipoprotein E receptor is involved in cellular recognition and internalization of these lipoproteins. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.
Uniprot IDB1AMT8
Protein Accession #NP_059992
Nucleotide Accession #NM_017522
Protein Size (# AA)700
Molecular Weight74kDa
Protein InteractionsUBC; MYLIP; RELN; APOE; GRIN1; SNX17; DAB1; DLG4; CLU; APOH; LRPAP1; SYNJ2BP; MAPK8IP2; GIPC1; ANAPC10; NOS1AP; MAPK8IP1; ITGB1BP1; SCN3A; APBA2;
  1. What is the species homology for "LRP8 Antibody - middle region (ARP44723_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish".

  2. How long will it take to receive "LRP8 Antibody - middle region (ARP44723_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "LRP8 Antibody - middle region (ARP44723_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "LRP8 Antibody - middle region (ARP44723_P050)"?

    This target may also be called "MCI1, LRP-8, APOER2, HSZ75190" in publications.

  5. What is the shipping cost for "LRP8 Antibody - middle region (ARP44723_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "LRP8 Antibody - middle region (ARP44723_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "LRP8 Antibody - middle region (ARP44723_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "74kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "LRP8 Antibody - middle region (ARP44723_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "LRP8"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "LRP8"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "LRP8"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "LRP8"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "LRP8"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "LRP8"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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