LONP1 Antibody - middle region (OAAB15092)

Catalog No: OAAB15092

Size:400ul

LONP1 Antibody (Center) (Cat. # OAAB15092) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the LONP1 antibody detected the LONP1 protein (arrow).

LONP1 is strongly supported by BioGPS gene expression data to be expressed in Hela

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB
  Function: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single- stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site- specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein
  Cellular Location: Mitochondrion matrix.
  Tissue Location: Duodenum, heart, lung and liver, but not thymus
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This LONP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids from the Central region of human LONP1.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Predicted Homology Based on Immunogen Sequence: Cow; Human; Mouse; Rat
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  LONP1 is strongly supported by BioGPS gene expression data to be expressed in Hela

• Intended Use: LONP1 (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
• Application Info: WB: 1:1000

Target Info

• Gene Symbol: LONP1
• Alias Symbols: LON, LONP, PIM1, hLON, LonHS, CODASS, PRSS15
• NCBI Gene Id: 9361
• Protein Name: Lon protease homolog, mitochondrial
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: P36776
• Protein Accession #: NP_001263408.1
• Molecular Weight: 106489 Da