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KIF2A antibody - N-terminal region (ARP33902_P050)

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Description of Target:
KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].
Gene Symbol:
KIF2A
Official Gene Full Name:
Kinesin heavy chain member 2A
NCBI Gene Id:
3796
Alias Symbols:
HK2; KIF2
Tissue Tool:
Find tissues and cell lines supported to express KIF2A.
Protein Accession #:
NP_004511
Nucleotide Accession#:
NM_004520
Swissprot Id:
O00139
Host:
Rabbit
Clonality:
Polyclonal
Protein Name:
Kinesin-like protein KIF2A
Protein Size (# AA):
706
Molecular Weight:
80kDa
Application:
IHC, WB
Partner Proteins:
PLEKHM2, TRAK1, KIF5A, KLC3, KTN1, NCOA2, NDRG1, RRBP1, SNAP23, SNAP25, SYBU, YWHAB, YWHAG, YWHAQ, YWHAZ, DTNB, KIF5C, KLC1, KLC2, MARK2, MEPCE, NME2, SFN, SNAP23, SNAP25, USPL1, VDAC1, YWHAB, YWHAG, YWHAH, YWHAQ, YWHAZ
Immunogen:
The immunogen for anti-KIF2A antibody: synthetic peptide directed towards the N terminal of human KIF2A
Product Format:
Lyophilized powder
Purification:
Affinity Purified
Complete computational species homology data:
KIF2A antibody - N-terminal region (ARP33902_P050)
Predicted Homology Based on Immunogen Sequence:
Human: 100%; Dog: 93%; Pig: 93%; Rat: 93%; Rabbit: 93%; Guinea pig: 93%; Horse: 86%; Bovine: 86%; Mouse: 79%
Species Reactivity:
Human, Rat, Dog, Rabbit, Guinea pig, Bovine, Horse, Mouse
Datasheets / Downloads:
Printable datasheet for
anti-KIF2A antibody
- ARP33902_P050
Peptide Sequence:
Synthetic peptide located within the following region: IEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARPS
Blocking Peptide:
For anti-KIF2A antibody is Catalog # AAP33902 (Previous Catalog # AAPP04973)
Key Reference:
Jang,C.Y., (2008) J. Cell Biol. 181 (2), 255-267
Reconstitution and Storage:
Add 50 ul of distilled water. Final anti-KIF2A antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
 
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