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100 ul
$289.00
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KIF2A antibody - N-terminal region (ARP33902_P050)

Receive a free positive control (AHL001) when you purchase this antibody. Use the promotion code 'freecontrol' when placing your order.
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Description of Target:
KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].
Gene Symbol:
KIF2A
Official Gene Full Name:
Kinesin heavy chain member 2A
NCBI Gene Id:
3796
Alias Symbols:
HK2; KIF2
Tissue Tool:
Find tissues and cell lines supported to express KIF2A.
Protein Accession #:
NP_004511
Nucleotide Accession#:
NM_004520
Swissprot Id:
O00139
Host:
Rabbit
Clonality:
Polyclonal
Protein Name:
Kinesin-like protein KIF2A
Protein Size (# AA):
706
Molecular Weight:
80kDa
Application:
IHC, WB
Protein Interactions:
FAM13C; MRPL53; LARP1B; KIF2A; UBC; WWOX; STK4; HIST3H3; NOTCH1; HDGF; KLC2; CLSTN1; KLC1;
Immunogen:
The immunogen for anti-KIF2A antibody: synthetic peptide directed towards the N terminal of human KIF2A
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Purification:
Affinity Purified
Complete computational species homology data:
KIF2A antibody - N-terminal region (ARP33902_P050)
Predicted Homology Based on Immunogen Sequence:
Human: 100%; Dog: 93%; Pig: 93%; Rat: 93%; Rabbit: 93%; Guinea pig: 93%; Horse: 86%; Bovine: 86%; Mouse: 79%
Species Reactivity:
Human, Rat, Dog, Rabbit, Guinea pig, Bovine, Horse, Mouse
Datasheets / Downloads:
Printable datasheet for
anti-KIF2A antibody
- ARP33902_P050
Peptide Sequence:
Synthetic peptide located within the following region: IEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARPS
Blocking Peptide:
For anti-KIF2A antibody is Catalog # AAP33902 (Previous Catalog # AAPP04973)
Target Reference:
Jang,C.Y., (2008) J. Cell Biol. 181 (2), 255-267
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Product Protocols: KIF2A antibody tested with Human Hepg2 Cells (ARP33902_P050)

Aviva Systems Biology is the original manufacturer of this KIF2A antibody (ARP33902_P050)

Click here to view the KIF2A antibody Western Blot Protocol

Product Datasheet Link: KIF2A antibody (ARP33902_P050)

WB Suggested Anti-KIF2A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2

Western Blot image:


Description of Target: KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].

Questions pertaining to this data can be directed to techsupport@avivasysbio.com

Aviva Systems Biology’s KIF2A antibody (ARP33902_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.

To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.

All of Aviva’s products are guaranteed for the applications and experimental sample types mentioned in the datasheet below. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com

 
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