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KIF2A antibody - N-terminal region (ARP33902_P050)

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100 ul
$289.00
In Stock

Conjugation Options

ARP33902_P050-FITC Conjugated

ARP33902_P050-HRP Conjugated

ARP33902_P050-Biotin Conjugated

Gene Symbol:
KIF2A
NCBI Gene Id:
3796
Official Gene Full Name:
Kinesin heavy chain member 2A
Protein Name:
Kinesin-like protein KIF2A
Swissprot Id:
O00139
Protein Accession #:
NP_004511
Nucleotide Accession #:
NM_004520
Alias Symbols:
HK2, KIF2
Replacement Item:
This antibody may replace item sc-136396, HPA004716
Description of Target:
KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].
Protein Size (# AA):
706
Molecular Weight:
80kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express KIF2A.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express KIF2A.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human KIF2A
Species Reactivity:
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 86%; Dog: 93%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 93%
Complete computational species homology data:
Anti-KIF2A (ARP33902_P050)
Peptide Sequence:
Synthetic peptide located within the following region: IEPSPETPPPPASSAKVNKIVKNRRTVASIKNDPPSRDNRVVGSARARPS
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
FAM13C; MRPL53; LARP1B; KIF2A; UBC; WWOX; STK4; HIST3H3; NOTCH1; HDGF; KLC2; CLSTN1; KLC1;
Blocking Peptide:
For anti-KIF2A (ARP33902_P050) antibody is Catalog # AAP33902 (Previous Catalog # AAPP04973)
Datasheets / Downloads:
Printable datasheet for anti-KIF2A (ARP33902_P050) antibody
Target Reference:
Jang,C.Y., (2008) J. Cell Biol. 181 (2), 255-267

Product Protocols: KIF2A antibody tested with Human Hepg2 Cells (ARP33902_P050)

Aviva Systems Biology is the original manufacturer of this KIF2A antibody (ARP33902_P050)

Click here to view the KIF2A antibody Western Blot Protocol

Product Datasheet Link: KIF2A antibody (ARP33902_P050)

WB Suggested Anti-KIF2A Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: HepG2

Western Blot image:


Description of Target: KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].

Questions pertaining to this data can be directed to techsupport@avivasysbio.com

Aviva Systems Biology’s KIF2A antibody (ARP33902_P050) has been tested using other cell lysates and tissues. To obtain more data about this antibody please email us at info@avivasysbio.com.

To order by phone call us at (888) 880-0001, fax us at (858) 552-6975 or send an email to info@avivasysbio.com. Aviva manufactures this antibody so we can offer the best price. Please contact us to request pricing information.

All of Aviva’s products are guaranteed for the applications and experimental sample types mentioned in the datasheet below. Are you curious if this product will work for you? Please contact us at techsupport@avivasysbio.com

 
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