KCNJ10 Antibody - middle region (OAAB12659)

Catalog No: OAAB12659

Size:400ul

KCNJ10 Antibody (Center) (Cat. # OAAB12659) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the KCNJ10 antibody detected the KCNJ10 protein (arrow).

KCNJ10 is strongly supported by BioGPS gene expression data to be expressed in HL60

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB
• Additional Information: Precautions: KCNJ10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity)
  Cellular Location: Membrane; Multi-pass membrane protein.
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This KCNJ10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-230 amino acids from the Central region of human KCNJ10.
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Sample Type Confirmation:

  KCNJ10 is strongly supported by BioGPS gene expression data to be expressed in HL60

• Application Info: WB: 1:2000
  WB: 1:1000

Target Info

• Gene Symbol: KCNJ10
• Alias Symbols: KIR1.2, KIR4.1, SESAME, BIRK-10, KCNJ13-PEN
• NCBI Gene Id: 3766
• Protein Name: ATP-sensitive inward rectifier potassium channel 10
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: P78508
• Protein Accession #: NP_002232.2
• Molecular Weight: 42508 Da