Catalog No: OASG04012
Size:100 uL
Price: $239.00
SKU
OASG04012
Availability: Domestic: within 2-3 weeks delivery | International: 2-3 weeks
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JAK3 Antibody (Phospho-Tyr785) (OASG04012)

Datasheets/ManualsPrintable datasheet for anti-JAK3 (OASG04012) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquidPBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationWB, IHC, ELISA
Additional InformationCellular Localization: Endomembrane system, cytoplasm
Tissue Specificity: In NK cells and an NK-like cell line but not in resting T-cells or in other tissues. The S-form is more commonly seen in hematopoietic lines, whereas the B-form is detected in cells both of hematopoietic and epithelial origins.
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
ImmunogenSynthesized peptide derived from human JAK3 around the phosphorylation site of Y785. Location: 720-800aa.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Target Post-Translational ModificationPhospho-Tyr785
SpecificityPhospho-JAK3 (Tyr785) Polyclonal Antibody detects endogenous levels of JAK3 protein only when phosphorylated at Y785.
Application InfoWB: 1:500~2000
IHC: 1:100~300
ELISA: 1:5000
Gene SymbolJAK3
Gene Full NameJanus kinase 3
Alias SymbolsJAKL, LJAK, JAK-3, L-JAK, JAK3_HUMAN
NCBI Gene Id3718; 16453;
Description of TargetThe protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Uniprot IDP52333, Q62137, Q63272
Molecular Weight125 kDa
  1. What is the species homology for "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?

    This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".

  3. What buffer format is "JAK3 Antibody (Phospho-Tyr785) (OASG04012)" provided in?

    This item is provided in "LiquidPBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?

    This target may also be called "JAKL, LJAK, JAK-3, L-JAK, JAK3_HUMAN" in publications.

  5. What is the shipping cost for "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "125 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "JAK3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "JAK3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "JAK3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "JAK3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "JAK3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "JAK3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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