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- $55: Antibody & Protein in US
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Datasheets/Manuals | Printable datasheet for anti-JAK3 (OASG04012) antibody |
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Predicted Species Reactivity | Human, Mouse, Rat |
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Product Format | LiquidPBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Application | WB, IHC, ELISA |
Additional Information | Cellular Localization: Endomembrane system, cytoplasm Tissue Specificity: In NK cells and an NK-like cell line but not in resting T-cells or in other tissues. The S-form is more commonly seen in hematopoietic lines, whereas the B-form is detected in cells both of hematopoietic and epithelial origins. |
Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
Immunogen | Synthesized peptide derived from human JAK3 around the phosphorylation site of Y785. Location: 720-800aa. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration | 1 mg/ml |
Target Post-Translational Modification | Phospho-Tyr785 |
Specificity | Phospho-JAK3 (Tyr785) Polyclonal Antibody detects endogenous levels of JAK3 protein only when phosphorylated at Y785. |
Application Info | WB: 1:500~2000 IHC: 1:100~300 ELISA: 1:5000 |
Gene Symbol | JAK3 |
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Gene Full Name | Janus kinase 3 |
Alias Symbols | JAKL, LJAK, JAK-3, L-JAK, JAK3_HUMAN |
NCBI Gene Id | 3718; 16453; |
Description of Target | The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). |
Uniprot ID | P52333, Q62137, Q63272 |
Molecular Weight | 125 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
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How long will it take to receive "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?
This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".
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What buffer format is "JAK3 Antibody (Phospho-Tyr785) (OASG04012)" provided in?
This item is provided in "LiquidPBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?
This target may also be called "JAKL, LJAK, JAK-3, L-JAK, JAK3_HUMAN" in publications.
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What is the shipping cost for "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "125 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "JAK3 Antibody (Phospho-Tyr785) (OASG04012)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "JAK3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "JAK3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "JAK3"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "JAK3"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "JAK3"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "JAK3"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.