ITGAX Antibody (OAGA00186)

Catalog No: OAGA00186

Size:100 ul

Sample(30 ug whole cell lysate)
A:H1299
B:Hep G2
7.5% SDS PAGE
OAGA00186 diluted at 1:1000

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Additional Information: Background: This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq]
  Positive Controls: H1299, HeLaS3, HepG2, Raji
  Cellular Localization: Membrane; Single-pass type I membrane protein
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 168 (P20702) of CD11c
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: ITGAX
• Gene Full Name: Integrin alpha-X
• Alias Symbols: CD11C, SLEB6
• NCBI Gene Id: 3687
• Protein Name: Integrin alpha-X
• Uniprot ID: P20702
• Protein Accession #: NP_000878.2
• Molecular Weight: 128 kDa