ITGAV Antibody - C-terminal region (ARP64575_P050)

Catalog No: ARP64575_P050

WB Suggested Anti-ITGAV Antibody
Titration: 1.0 ug/ml
Positive Control: PANC1 Whole Cell

Host: Rabbit
Target Name: ITGAV
Sample Type: Human Fetal Heart
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: ITGAV
Sample Type: Human Fetal Lung
Antibody Dilution: 1.0ug/ml

Host: Rabbit
Target Name: ITGAV
Sample Tissue: Human 293T Whole Cell
Antibody Dilution: 1ug/ml

Host: Mouse
Target Name: ITGAV
Sample Tissue: Mouse Heart
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human, Mouse
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ITGAV
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
• Peptide Sequence: Synthetic peptide located within the following region: PVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENG
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-ITGAV (ARP64575_P050) antibody is Catalog # AAP64575

Target Info

• Gene Symbol: ITGAV
• Alias Symbols: CD51, MSK8, VNRA, VTNR
• NCBI Gene Id: 3685
• Protein Name: Integrin alpha-V light chain Ensembl ENSP00000404291
• Description of Target: ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.
• Uniprot ID: E7EWZ6
• Protein Accession #: NP_001138471
• Nucleotide Accession #: NM_001144999
• Protein Size (# AA): 1002
• Molecular Weight: 100kDa
• Protein Interactions: UBC; EPHA2; THBS1; FN1; KRT3; MCAT; FBXO6; BCAR1; PXN; PHKA2; CSF1R; CBL; MMP2; ILK; PLP1; CALR; ANGPTL3; EDIL3; CYR61; PAK4; ITGB8; ADAM9; AUP1; CD47; PTK2; MMP14; P2RY2; L1CAM; AZGP1; TGFB1; THY1; F2R; PDGFRA; ITGB3; SPP1; ITGB5; ITGB6; ITGB1; NID1; ICA