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Catalog No: ARP50512_T100
Price: $0.00
SKU
ARP50512_T100
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Datasheets/ManualsPrintable datasheet for anti-ING1 (ARP50512_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human ING1
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 86%
Peptide SequenceSynthetic peptide located within the following region: EKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYCLCNQVSYGEMIGCD
Concentration1.0 mg/ml
Blocking PeptideFor anti-ING1 (ARP50512_T100) antibody is Catalog # AAP50512 (Previous Catalog # AAPS26411)
Sample Type Confirmation

There is BioGPS gene expression data showing that ING1 is expressed in HepG2

ReferenceAhmed,I.A., (2008) Colorectal Dis 10 (4), 344-351
Gene SymbolING1
Gene Full NameInhibitor of growth family, member 1
Alias Symbolsp33, p47, p33ING1, p24ING1c, p33ING1b, p47ING1a
NCBI Gene Id3621
Protein NameInhibitor of growth protein 1
Description of TargetING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
Uniprot IDQ5T9H0
Protein Accession #NP_937862
Nucleotide Accession #NM_198219
Protein Size (# AA)279
Molecular Weight32kDa
Protein InteractionsSIRT1; SIRT2; UBC; HDAC1; KIAA0101; PCNA; RBP1; RBBP7; RBBP4; HDAC2; BRMS1L; SIN3A; BRMS1; SAP30; ELAVL1; SMURF1; COPS2; NQO1; HIST2H3C; MRGBP; YWHAZ; YWHAH; YWHAG; YWHAE; YWHAB; KPNA2; KPNB1; YWHAQ; SFN; ESR1; LMNA; CDKN2A; TP53; KAT2B; DMAP1; EP300; HHT
  1. What is the species homology for "ING1 Antibody - C-terminal region (ARP50512_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish".

  2. How long will it take to receive "ING1 Antibody - C-terminal region (ARP50512_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "ING1 Antibody - C-terminal region (ARP50512_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ING1 Antibody - C-terminal region (ARP50512_T100)"?

    This target may also be called "p33, p47, p33ING1, p24ING1c, p33ING1b, p47ING1a" in publications.

  5. What is the shipping cost for "ING1 Antibody - C-terminal region (ARP50512_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ING1 Antibody - C-terminal region (ARP50512_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ING1 Antibody - C-terminal region (ARP50512_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "32kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ING1 Antibody - C-terminal region (ARP50512_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ING1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ING1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ING1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ING1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ING1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ING1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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