INCENP Antibody - C-terminal region (ARP63541_P050)

Catalog No: ARP63541_P050

Host: Rabbit
Target Name: INCENP
Sample Type: Fetal Lung lysates
Antibody Dilution: 1.0ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human INCENP
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Horse: 85%; Human: 100%; Mouse: 86%; Pig: 92%; Rabbit: 92%; Rat: 86%
• Peptide Sequence: Synthetic peptide located within the following region: RELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACT
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-INCENP (ARP63541_P050) antibody is Catalog # AAP63541

Target Info

• Gene Symbol: INCENP
• Gene Full Name: inner centromere protein antigens 135/155kDa
• Alias Symbols: INCENP,
• NCBI Gene Id: 3619
• Protein Name: Inner centromere protein
• Description of Target: In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA, CENPB, CENPC1, and CENPD. The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle. These include CENPE; MCAK; KID; cytoplasmic dynein; CliPs; and CENPF/mitosin. The inner centromere proteins (INCENPs), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis
• Uniprot ID: Q9NQS7
• Protein Accession #: NP_064623
• Protein Size (# AA): 918
• Molecular Weight: 100kDa
• Protein Interactions: FLOT1; AURKB; HECW2; AURKC; AURKA; UBC; CDCA8; BIRC5; CBX5; HIST2H3C; SIRT7; Incenp; TUBA1A; EVI5; H2AFZ; SGOL1;