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Datasheets/Manuals | Printable datasheet for anti-IMPDH2 antibody - OAAB04410 |
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Predicted Species Reactivity | Human |
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Product Format | Liquid PBS with 0.09% (W/V) sodium azide. |
Clonality | Polyclonal |
Isotype | Rabbit Ig |
Host | Rabbit |
Application | WB, IHC-P, FC |
:: | Cellular Location: Cytoplasm, Nucleus Tissue Location: IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor |
Reconstitution and Storage | Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles. |
Immunogen | This IMPDH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-210 amino acids from the Central region of human IMPDH2. |
Purification | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Predicted Homology Based on Immunogen Sequence | Bovine, Mouse, Rat, Hamster, Zebrafish |
Concentration | Approximately 0.5mg/ml. Actual concentration varies with each lot. |
Sample Type Confirmation | IMPDH2 is strongly supported by BioGPS gene expression data to be expressed in MCF7, NCI-H460 |
Application Info | WB: 1:1000 IHC-P: 1:50~100 FC: 1:10~50 |
Other Applications Image 1 Data | IMPDH2 Antibody (Center) flow cytometric analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Gene Symbol | IMPDH2 |
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Alias Symbols | IMPD2, IMPDH-II |
NCBI Gene Id | 3615 |
Protein Name | Inosine-5'-monophosphate dehydrogenase 2 |
Description of Target | IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. Its gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |
Uniprot ID | P12268 |
Protein Accession # | NP_000875.2 |
Molecular Weight | 56 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "IMPDH2 Antibody - middle region (OAAB04410)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "IMPDH2 Antibody - middle region (OAAB04410)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "IMPDH2 Antibody - middle region (OAAB04410)" provided in?
This item is provided in "Liquid PBS with 0.09% (W/V) sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IMPDH2 Antibody - middle region (OAAB04410)"?
This target may also be called "IMPD2, IMPDH-II" in publications.
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What is the shipping cost for "IMPDH2 Antibody - middle region (OAAB04410)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "IMPDH2 Antibody - middle region (OAAB04410)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "IMPDH2 Antibody - middle region (OAAB04410)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "56 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IMPDH2 Antibody - middle region (OAAB04410)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "IMPDH2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "IMPDH2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "IMPDH2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "IMPDH2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "IMPDH2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "IMPDH2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.