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Datasheets/Manuals | Printable datasheet for IL23A Antibody (OAPB00407) (OAPB00407) |
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Predicted Species Reactivity | Guinea Pig|Horse|Human|Mouse|Porcine|Rat |
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Product Format | Liquid. IL-23 Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot |
:: | Buffer: Antibody is supplied in PBS containing 0.02% sodium azide. |
Reconstitution and Storage | 2°C to 8°C |
Immunogen | Anti-IL-23 antibody (3795) was raised against a peptide corresponding to 17 amino acids near the amino terminus of human IL-23. The immunogen is located within amino acids 40 - 90 of IL-23. |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Human; Mouse |
Concentration | 1 mg/ml |
Blocking Peptide | For anti-IL23A (OAPB00407) antibody is Catalog # OEPB02507 |
Application Info | IL-23 antibody can be used for the detection of IL-23 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user) |
Reference | Hunter CA. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat. Rev. Immunol. 2005; 5:521-31.;Oppmann B, Lesley R, Blom B, et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000; 13:715-25.;Sheibanie AF, Tadmori I, Jing H, et al. Prostaglandin ED induces IL-23 production in bone marrow-derived dendritic cells. FASEB J. 2004; 18:1318-20.;Pirhonen J, Matikainen S, Julkunen I. Regulation of virus-induced IL-12 and IL-23 expression in human macrophages. J. Immunol. 2002; 169:5673-8. |
Gene Symbol | IL23A |
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Gene Full Name | interleukin 23 subunit alpha |
Alias Symbols | IL-23;IL-23 subunit alpha;IL-23A;IL-23-A;IL-23p19;IL23P19;interleukin 23 p19 subunit;interleukin 23, alpha subunit p19;interleukin-23 subunit alpha;interleukin-23 subunit p19;interleukin-six, G-CSF related factor;JKA3 induced upon T-cell activation;P19;SGRF. |
NCBI Gene Id | 51561 |
Protein Name | Interleukin 23, alpha subunit p19 [Homo sapiens]|Interleukin-23 subunit alpha |
Description of Target | Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
Uniprot ID | Q9NPF7 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/AAH66268 |
Nucleotide Accession # | NM_016584.2 |
Molecular Weight | Predicted: 21kD Observed: 22 kD |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "IL23A Antibody (OAPB00407)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Guinea Pig|Horse|Human|Mouse|Porcine|Rat".
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How long will it take to receive "IL23A Antibody (OAPB00407)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "IL23A Antibody (OAPB00407)" provided in?
This item is provided in "Liquid. IL-23 Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IL23A Antibody (OAPB00407)"?
This target may also be called "IL-23;IL-23 subunit alpha;IL-23A;IL-23-A;IL-23p19;IL23P19;interleukin 23 p19 subunit;interleukin 23, alpha subunit p19;interleukin-23 subunit alpha;interleukin-23 subunit p19;interleukin-six, G-CSF related factor;JKA3 induced upon T-cell activation;P19;SGRF." in publications.
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What is the shipping cost for "IL23A Antibody (OAPB00407)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "IL23A Antibody (OAPB00407)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "IL23A Antibody (OAPB00407)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "Predicted: 21kD Observed: 22 kD".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IL23A Antibody (OAPB00407)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "IL23A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "IL23A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "IL23A"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "IL23A"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "IL23A"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "IL23A"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.