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Datasheets/Manuals | Printable datasheet for IL23A Antibody (OAPB00406) (OAPB00406) |
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Predicted Species Reactivity | Guinea Pig|Horse|Human|Mouse|Rat |
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Product Format | Liquid. IL-23 Antibody is supplied in PBS containing 0.02% sodium azide. |
Clonality | Polyclonal |
Host | Rabbit |
Conjugation | Unconjugated |
Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot |
Additional Information | Raji Cell Lysate (OCPB00175) |
:: | Buffer: Antibody is supplied in PBS containing 0.02% sodium azide. |
Reconstitution and Storage | IL-23 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
Immunogen | Anti-IL-23 antibody (3793) was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of mature human IL-23. The immunogen is located the last 50 amino acids of IL-23. |
Purification | Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Human; Mouse |
Concentration | 1 mg/ml |
Blocking Peptide | For anti-IL23A (OAPB00406) antibody is Catalog # OEPB02506 |
Application Info | IL-23 antibody can be used for the detection of IL-23 by Western blot at 1 ug/mL. Antibody can also be used for immunocytochemistry starting at 10 ug/mL and immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL. |
Other Applications Image 1 Data | Immunocytochemistry of IL-23 in Raji cells with IL-23 antibody at 10 ug/mL. |
Reference | Hunter CA. New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions. Nat. Rev. Immunol. 2005; 5:521-31.;Oppmann B, Lesley R, Blom B, et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 2000; 13:715-25.;Sheibanie AF, Tadmori I, Jing H, et al. Prostaglandin ED induces IL-23 production in bone marrow-derived dendritic cells. FASEB J. 2004; 18:1318-20.;Pirhonen J, Matikainen S, Julkunen I. Regulation of virus-induced IL-12 and IL-23 expression in human macrophages. J. Immunol. 2002; 169:5673-8. |
Gene Symbol | IL23A |
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Gene Full Name | interleukin 23 subunit alpha |
Alias Symbols | IL-23;IL-23 subunit alpha;IL-23A;IL-23-A;IL-23p19;IL23P19;interleukin 23 p19 subunit;interleukin 23, alpha subunit p19;interleukin-23 subunit alpha;interleukin-23 subunit p19;interleukin-six, G-CSF related factor;JKA3 induced upon T-cell activation;P19;SGRF. |
NCBI Gene Id | 51561 |
Protein Name | Interleukin 23, alpha subunit p19 [Homo sapiens]|Interleukin-23 subunit alpha |
Description of Target | Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
Uniprot ID | Q9NPF7 |
Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/AAH66268 |
Nucleotide Accession # | NM_016584.2 |
Molecular Weight | Predicted: 21kD Observed: 22 kD |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "IL23A Antibody (OAPB00406)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Guinea Pig|Horse|Human|Mouse|Rat".
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How long will it take to receive "IL23A Antibody (OAPB00406)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
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What buffer format is "IL23A Antibody (OAPB00406)" provided in?
This item is provided in "Liquid. IL-23 Antibody is supplied in PBS containing 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "IL23A Antibody (OAPB00406)"?
This target may also be called "IL-23;IL-23 subunit alpha;IL-23A;IL-23-A;IL-23p19;IL23P19;interleukin 23 p19 subunit;interleukin 23, alpha subunit p19;interleukin-23 subunit alpha;interleukin-23 subunit p19;interleukin-six, G-CSF related factor;JKA3 induced upon T-cell activation;P19;SGRF." in publications.
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What is the shipping cost for "IL23A Antibody (OAPB00406)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "IL23A Antibody (OAPB00406)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "IL23A Antibody (OAPB00406)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "Predicted: 21kD Observed: 22 kD".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "IL23A Antibody (OAPB00406)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "IL23A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "IL23A"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "IL23A"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "IL23A"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "IL23A"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "IL23A"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.