Catalog No: ARP40658_P050
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ARP40658_P050
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Datasheets/ManualsPrintable datasheet for anti-IGF2BP1 (ARP40658_P050) antibody
Product Info
Tested Species ReactivityHuman, Rat
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human IGF2BP1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%
Peptide SequenceSynthetic peptide located within the following region: PDEQIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPT
Concentration0.5 mg/ml
Blocking PeptideFor anti-IGF2BP1 (ARP40658_P050) antibody is Catalog # AAP40658 (Previous Catalog # AAPY00910)
ReferenceIoannidis,P., (2005) J. Biol. Chem. 280 (20), 20086-20093
Publications

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. Mol Cell. 74, 701-712.e9 (2019). 30948266

Description
Gene SymbolIGF2BP1
Gene Full NameInsulin-like growth factor 2 mRNA binding protein 1
Alias SymbolsIMP1, ZBP1, CRDBP, IMP-1, CRD-BP, VICKZ1
NCBI Gene Id10642
Protein NameInsulin-like growth factor 2 mRNA-binding protein 1
Description of TargetIGF2BP1 is a member of the IGF-II mRNA-binding protein (IMP) family. The protein contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation.This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation.This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDQ9NZI8
Protein Accession #NP_006537
Nucleotide Accession #NM_006546
Protein Size (# AA)577
Molecular Weight63kDa
Protein InteractionsHAUS2; TUBGCP2; TUBGCP3; TP53; AURKA; CDKN1A; TUBGCP4; CEP250; IVNS1ABP; STAU1; UBC; WWOX; PARK2; FBXO6; BAG3; PAN2; VCAM1; ITGA4; IFIT1; GRB2; FN1; CBX6; CBX8; SYNCRIP; BIRC2; CAND1; COPS5; CUL1; CUL2; CUL3; CUL4A; CUL4B; CUL5; NEDD8; gag; BTRC; ARRB2; Y
  1. What is the species homology for "IGF2BP1 Antibody - N-terminal region (ARP40658_P050)"?

    The tested species reactivity for this item is "Human, Rat". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep".

  2. How long will it take to receive "IGF2BP1 Antibody - N-terminal region (ARP40658_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "IGF2BP1 Antibody - N-terminal region (ARP40658_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "IGF2BP1 Antibody - N-terminal region (ARP40658_P050)"?

    This target may also be called "IMP1, ZBP1, CRDBP, IMP-1, CRD-BP, VICKZ1" in publications.

  5. What is the shipping cost for "IGF2BP1 Antibody - N-terminal region (ARP40658_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "IGF2BP1 Antibody - N-terminal region (ARP40658_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "IGF2BP1 Antibody - N-terminal region (ARP40658_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "63kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "IGF2BP1 Antibody - N-terminal region (ARP40658_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "IGF2BP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "IGF2BP1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "IGF2BP1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "IGF2BP1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "IGF2BP1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "IGF2BP1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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