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Datasheets/Manuals | Printable datasheet for HTR1B Antibody (OAAF02797) |
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Predicted Species Reactivity | Human|Mouse|Rat |
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Product Format | Liquid PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Application | Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot |
Reconstitution and Storage | -20°C |
Immunogen | The antiserum was produced against synthesized peptide derived from human 5-HT-1B. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration | 1 mg/ml |
Specificity | 5-HT-1B antibody detects endogenous levels of total 5-HT-1B protein. |
Application Info | WB: 1/500 - 1/2000 IHC: 1/100 - 1/300 IF: 1/200 - 1/1000 ELISA: 1/10000 |
Reference | Weinshank R.L., Proc. Natl. Acad. Sci. U.S.A. 89:3630-3634(1992). Demchyshyn L., Proc. Natl. Acad. Sci. U.S.A. 89:5522-5526(1992). Mochizuki D., Biochem. Biophys. Res. Commun. 185:517-523(1992). |
Gene Symbol | HTR1B |
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Gene Full Name | 5-hydroxytryptamine receptor 1B |
Alias Symbols | 5-HT1B;5-HT-1B;5-HT1DB;5-HT-1D-beta;5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled;5-hydroxytryptamine receptor 1B;HTR1D2;HTR1DB;S12;serotonin 1D beta receptor;serotonin receptor 1B. |
NCBI Gene Id | 3351 |
Protein Name | 5-hydroxytryptamine receptor 1B |
Description of Target | G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries. |
Uniprot ID | P28222 |
Protein Accession # | NP_000854.1 |
Molecular Weight | 43 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "HTR1B Antibody (OAAF02797)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".
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How long will it take to receive "HTR1B Antibody (OAAF02797)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "HTR1B Antibody (OAAF02797)" provided in?
This item is provided in "Liquid PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "HTR1B Antibody (OAAF02797)"?
This target may also be called "5-HT1B;5-HT-1B;5-HT1DB;5-HT-1D-beta;5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled;5-hydroxytryptamine receptor 1B;HTR1D2;HTR1DB;S12;serotonin 1D beta receptor;serotonin receptor 1B." in publications.
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What is the shipping cost for "HTR1B Antibody (OAAF02797)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "HTR1B Antibody (OAAF02797)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "HTR1B Antibody (OAAF02797)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "43 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "HTR1B Antibody (OAAF02797)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "HTR1B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "HTR1B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "HTR1B"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "HTR1B"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "HTR1B"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "HTR1B"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.