HIST1H3A Antibody - N-terminal region (ARP60982_P050)

Catalog No: ARP60982_P050

WB Suggested Anti-HIST1H3A Antibody
Titration: 1.0 ug/ml
Positive Control: Jurkat Whole Cell

Host: Rabbit
Target Name: HIST1H3A
Sample Type: Human 721_B
Antibody Dilution: 1.0ug/mlHIST1H3A is supported by BioGPS gene expression data to be expressed in 721_B

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Pig, Yeast, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HIST1H3A
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: KQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRR
• Concentration: 0.5 mg/ml
• Blocking Peptide: Catalog # AAP60982 (Previous Catalog # AAPP47121)
• Sample Type Confirmation:

  HIST1H3A is supported by BioGPS gene expression data to be expressed in 721_B

Target Info

• Gene Symbol: HIST1H3A
• Gene Full Name: Histone cluster 1, H3a
• Alias Symbols: H3/A, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, H3C10, H3C11, H3C12, HIST1H3A
• NCBI Gene Id: 8350
• Protein Name: Histone H3.1
• Description of Target: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
• Uniprot ID: P68431
• Protein Accession #: NP_003520
• Nucleotide Accession #: NM_003529
• Protein Size (# AA): 136
• Molecular Weight: 15kDa
• Protein Interactions: WHSC1; SETD1A; FBLIM1; PRDM2; PRDM6; UBC; H2AFY; H2AFX; HIST1H1B; HIST1H1E; HIST1H1C; BAZ1B; HIST1H2AG; SMARCA5; HIST1H4A; HDAC2; UHRF1; L3MBTL2; GRB2; IRF1; HDAC11; AURKC; RPS6KA3; PAK1; ATXN1; ITGA4; env; CHAF1B; ASF1B; ASF1A; AURKB; CHAF1A; EP300; LRRK