GRIN2A Antibody (OABF01255)

Catalog No: OABF01255

Size:100UL

Formalin-fixed and paraffin embedded rat skin labeled with Rabbit Anti NR2A/NMDAR2A Polyclonal Antibody, Unconjugated (OABF01255) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Formalin-fixed and paraffin embedded rat skin labeled with Rabbit Anti NR2A/NMDAR2A Polyclonal Antibody, Unconjugated (OABF01255) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti NR2A/NMDAR2A Polyclonal Antibody, Unconjugated (OABF01255) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Formalin-fixed and paraffin-embedded rat brain labeled with Anti-NR2A/NMDAR2A Polyclonal Antibody, Unconjugated (OABF01255) 1:200, overnight at 4C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37C.

Product Info

• Predicted Species Reactivity: Bovine|Chicken|Dog|Horse|Human|Mouse|Porcine|Rabbit|Rat
• Product Format: Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Western blot
• Additional Information: Subcellular location: Cytoplasm
• Reconstitution and Storage: -20°C
• Immunogen: KLH conjugated synthetic peptide derived from human NMDAR2A
• Purification: Protein A Purified
• Concentration: 1 ug/ul
• Application Info: WB: 1:100 - 1000
  IHC-P: : 1:100 - 500

Target Info

• Gene Symbol: GRIN2A
• Gene Full Name: glutamate ionotropic receptor NMDA type subunit 2A
• Alias Symbols: EPND;FESD;GluN2A;Glutamate [NMDA] receptor subunit epsilon-1;glutamate ionotropic receptor NMDA 2A;glutamate receptor ionotropic, NMDA 2A;glutamate receptor, ionotropic, N-methyl D-aspartate 2A;LKS;NMDAR2A;N-methyl D-aspartate receptor subtype 2A;N-methyl-D-aspartate receptor channel, subunit epsilon-1;N-methyl-D-aspartate receptor subunit 2A;NR2A.
• NCBI Gene Id: 2903
• Protein Name: Glutamate receptor ionotropic, NMDA 2A
• Description of Target: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:8768735, PubMed:26919761, PubMed:26875626, PubMed:28105280). Sensitivity to glutamate and channel kinetics depend on the subunit composition; channels containing GRIN1 and GRIN2A have higher sensitivity to glutamate and faster kinetics than channels formed by GRIN1 and GRIN2B (PubMed:26919761, PubMed:26875626). Contributes to the slow phase of excitatory postsynaptic current, long-term synaptic potentiation, and learning (By similarity).
• Uniprot ID: Q12879