GPX2 Antibody (OAEB01607)

Catalog No: OAEB01607 (Formerly GWB-6E56EC)

Size:100UG

OAEB01607 staining (0.5ug/ml) of Human Liver lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Product Info

• Predicted Species Reactivity: Bovine|Dog|Human|Mouse|Porcine|Rat
• Product Format: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Clonality: Polyclonal
• Host: Goat
• Application: WB
• Additional Information: Reactivity Info: Tested: Human; Expected: Human, Mouse, Rat, Dog, Pig, Cow
• Reconstitution and Storage: Aliquot and store at -20C. Minimize freezing and thawing.
• Immunogen: GPX2
• Purification: Ammonium Sulfate Precipitated; Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human: 100%; Pig: 100%
• Peptide Sequence: C-SLDGEKVDFN
• Concentration: 0.5 mg/ml
• Purity: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Application Info: Peptide ELISA: antibody detection limit dilution 1:32000.
  Western Blot: Approx 24kDa band observed in Human Liver lysates (calculated MW of 21.9kDa according to NP_002074.2). Recommended concentration: 0.5-2ug/ml.
• Reference: * McGrath-Morrow S, Lauer T, Yee M, Neptune E, Podowski M, Thimmulappa RK, O'Reilly M, Biswal S.; Nrf2 increases survival and attenuates alveolar growth inhibition in neonatal mice exposed to hyperoxia.; Am J Physiol Lung Cell Mol Physiol. 2009 Apr;296(4):L565-73.; Pubmed 19151108
  * McGrath-Morrow S, Lauer T, Yee M, Neptune E, Podowski M, Thimmulappa RK, O'Reilly M, Biswal S.; Nrf2 increases survival and attenuates alveolar growth inhibition in neonatal mice exposed to hyperoxia.; Am J Physiol Lung Cell Mol Physiol. 2009 Apr;296(4):L565-73. Epub 2009 Jan 16.; Pubmed 19151108
  * Naiki-Ito A, Asamoto M, Hokaiwado N, Takahashi S, Yamashita H, Tsuda H, Ogawa K, Shirai T.; Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens.; Cancer Res. 2007 Dec 1;67(23):11353-8.; Pubmed 18056462
  * Naiki-Ito A, Asamoto M, Hokaiwado N, Takahashi S, Yamashita H, Tsuda H, Ogawa K, Shirai T.; Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens.; Cancer Res. 2007 Dec 1;67(23):11353-8.; Pubmed 18056462
  * Esworthy RS, Yang L, Frankel PH, Chu FF.; Epithelium-specific glutathione peroxidase, Gpx2, is involved in the prevention of intestinal inflammation in selenium-deficient mice.; J Nutr. 2005 Apr;135(4):740-5.; Pubmed 15795427

Target Info

• Gene Symbol: GPX2
• Gene Full Name: glutathione peroxidase 2
• Alias Symbols: gastrointestinal glutathione peroxidase;GI-GPx;glutathione peroxidase 2;glutathione peroxidase 2 (gastrointestinal);glutathione peroxidase-related protein 2;GPRP;GPRP-2;GPx-2;GPx-GI;GSHPx-2;GSHPX-GI;selenoprotein GPX2.
• NCBI Gene Id: 2877
• Protein Name: Glutathione peroxidase 2
• Uniprot ID: P18283
• Protein Accession #: NP_002074.2
• Molecular Weight: 21.9