Catalog No: ARP37665_T100
Price: $0.00
SKU
ARP37665_T100
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Datasheets/ManualsPrintable datasheet for anti-GPC3 (ARP37665_T100) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationIHC, WB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human GPC3
PurificationProtein A purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: FSTIHDSIQYVQKNAGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKVL
Concentration1.0 mg/ml
Blocking PeptideFor anti-GPC3 (ARP37665_T100) antibody is Catalog # AAP37665 (Previous Catalog # AAPP08963)
Enhanced Validation
WBY
SPR
YCHAROS
ReferenceBoily,G., et al., (2004) Br. J. Cancer 90 (8), 1606-1611
Publications

Bhave, V. S. et al. Regulation of liver growth by glypican 3, CD81, hedgehog, and Hhex. Am. J. Pathol. 183, 153-9 (2013). 23665349

Plasmodium parasite as an effective hepatocellular carcinoma antigen glypican-3 delivery vector. Oncotarget. 8, 24785-24796 (2017). 28445973

Description
Gene SymbolGPC3
Gene Full NameGlypican 3
Alias SymbolsSGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2
NCBI Gene Id2719
Protein NameGlypican-3
Description of TargetCell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome.
Uniprot IDP51654
Protein Accession #NP_004475
Nucleotide Accession #NM_004484
Protein Size (# AA)580
Molecular Weight66 kDa
Protein InteractionsUBC; WNT3A; WNT7B; IGF2; FGF2;
  1. What is the species homology for "GPC3 Antibody - middle region (ARP37665_T100)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "GPC3 Antibody - middle region (ARP37665_T100)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "GPC3 Antibody - middle region (ARP37665_T100)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "GPC3 Antibody - middle region (ARP37665_T100)"?

    This target may also be called "SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2" in publications.

  5. What is the shipping cost for "GPC3 Antibody - middle region (ARP37665_T100)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "GPC3 Antibody - middle region (ARP37665_T100)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "GPC3 Antibody - middle region (ARP37665_T100)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "66 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "GPC3 Antibody - middle region (ARP37665_T100)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "GPC3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "GPC3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "GPC3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "GPC3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "GPC3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "GPC3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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