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Datasheets/Manuals | Printable datasheet for Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441) |
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Predicted Species Reactivity | Dog|Human|Mouse|Porcine|Rat |
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Product Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing. |
Clonality | Polyclonal |
Host | Goat |
Application | IHC |
Additional Information | Reactivity Info: Tested: Human; Expected: Human, Mouse, Rat, Dog, Pig |
Reconstitution and Storage | Aliquot and store at -20C. Minimize freezing and thawing. |
Immunogen | TRPM7 |
Purification | Ammonium Sulfate Precipitated; Affinity Purified |
Predicted Homology Based on Immunogen Sequence | Cow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 85%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 92%; Sheep: 92% |
Peptide Sequence | C-TKESESTNSVRLML |
Concentration | 0.5 mg/ml |
Purity | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Application Info | Peptide ELISA: antibody detection limit dilution 1:16000. Western Blot: Approx. 150kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 213kDa according to NP_060142.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Clark et al PLoS ONE. 2008 Mar 26;3(3):e1876.; PMID: 18365021). Recommended concentration: 0.3- 1ug/ml. |
Reference | * Sun HS, Jackson MF, Martin LJ, Jansen K, Teves L, Cui H, Kiyonaka S, Mori Y, Jones M, Forder JP, Golde TE, Orser BA, Macdonald JF, Tymianski M.; Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia.; Nat Neurosci. 2009 Oct;12(10):1300-7. Epub 2009 Sep 6.; Pubmed 19734892 * Wei WL, Sun HS, Olah ME, Sun X, Czerwinska E, Czerwinski W, Mori Y, Orser BA, Xiong ZG, Jackson MF, Tymianski M, MacDonald JF.; TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations.; Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16323-8.; Pubmed 17913893 * Wei WL, Sun HS, Olah ME, Sun X, Czerwinska E, Czerwinski W, Mori Y, Orser BA, Xiong ZG, Jackson MF, Tymianski M, MacDonald JF.; TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations.; Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16323-8. Epub 2007 Oct 3.; Pubmed 17913893 * Kim BJ, Lim HH, Yang DK, Jun JY, Chang IY, Park CS, So I, Stanfield PR, Kim KW.; Melastatin-type transient receptor potential channel 7 is required for intestinal pacemaking activity.; Gastroenterology. 2005 Nov;129(5):1504-17.; Pubmed 16285951 * He Y, Yao G, Savoia C, Touyz RM.; Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II.; Circ Res. 2005 Feb 4;96(2):207-15.; Pubmed 15591230 * He Y, Yao G, Savoia C, Touyz RM.; Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II.; Circ Res. 2005 Feb 4;96(2):207-15. Epub 2004 Dec 9.; Pubmed 15591230 * Nadler MJ, Hermosura MC, Inabe K, Perraud AL, Zhu Q, Stokes AJ, Kurosaki T, Kinet JP, Penner R, Scharenberg AM, Fleig A.; LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability.; Nature 2001 May 31;411(6837):590-5; Pubmed 11385574 |
Gene Symbol | TRPM7 |
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Gene Full Name | transient receptor potential cation channel subfamily M member 7 |
Alias Symbols | ALSPDC;CHAK;CHAK1;channel-kinase 1;long transient receptor potential channel 7;LTRPC ion channel family member 7;LTrpC-7;LTRPC7;transient receptor potential cation channel subfamily M member 7;transient receptor potential-phospholipase C-interacting kinase;TRP-PLIK. |
NCBI Gene Id | 54822 |
Protein Name | Transient receptor potential cation channel subfamily M member 7 |
Uniprot ID | Q96QT4 |
Protein Accession # | NP_060142.3 |
Molecular Weight | 213; 213 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Dog|Human|Mouse|Porcine|Rat".
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How long will it take to receive "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)" provided in?
This item is provided in "Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?
This target may also be called "ALSPDC;CHAK;CHAK1;channel-kinase 1;long transient receptor potential channel 7;LTRPC ion channel family member 7;LTrpC-7;LTRPC7;transient receptor potential cation channel subfamily M member 7;transient receptor potential-phospholipase C-interacting kinase;TRP-PLIK." in publications.
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What is the shipping cost for "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "213; 213".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "TRPM7"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "TRPM7"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "TRPM7"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "TRPM7"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "TRPM7"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "TRPM7"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.