Catalog No: OAEB01441 (Formerly GWB-A9471F)
Size:100UG
Price: $379.00
SKU
OAEB01441
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
Bulk
Order
Aviva's
Satisfaction
Guarantee
Contact Us:
Shipping Info:
  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
  • Contact us for international orders.
Datasheets/ManualsPrintable datasheet for Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)
Product Info
Predicted Species ReactivityDog|Human|Mouse|Porcine|Rat
Product FormatSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
ClonalityPolyclonal
HostGoat
ApplicationIHC
Additional InformationReactivity Info: Tested: Human; Expected: Human, Mouse, Rat, Dog, Pig
Reconstitution and StorageAliquot and store at -20C. Minimize freezing and thawing.
ImmunogenTRPM7
PurificationAmmonium Sulfate Precipitated; Affinity Purified
Predicted Homology Based on Immunogen SequenceCow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 85%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 92%; Sheep: 92%
Peptide SequenceC-TKESESTNSVRLML
Concentration0.5 mg/ml
PurityPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Application InfoPeptide ELISA: antibody detection limit dilution 1:16000.
Western Blot: Approx. 150kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 213kDa according to NP_060142.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Clark et al PLoS ONE. 2008 Mar 26;3(3):e1876.; PMID: 18365021). Recommended concentration: 0.3- 1ug/ml.
Reference* Sun HS, Jackson MF, Martin LJ, Jansen K, Teves L, Cui H, Kiyonaka S, Mori Y, Jones M, Forder JP, Golde TE, Orser BA, Macdonald JF, Tymianski M.; Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia.; Nat Neurosci. 2009 Oct;12(10):1300-7. Epub 2009 Sep 6.; Pubmed 19734892
* Wei WL, Sun HS, Olah ME, Sun X, Czerwinska E, Czerwinski W, Mori Y, Orser BA, Xiong ZG, Jackson MF, Tymianski M, MacDonald JF.; TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations.; Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16323-8.; Pubmed 17913893
* Wei WL, Sun HS, Olah ME, Sun X, Czerwinska E, Czerwinski W, Mori Y, Orser BA, Xiong ZG, Jackson MF, Tymianski M, MacDonald JF.; TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations.; Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16323-8. Epub 2007 Oct 3.; Pubmed 17913893
* Kim BJ, Lim HH, Yang DK, Jun JY, Chang IY, Park CS, So I, Stanfield PR, Kim KW.; Melastatin-type transient receptor potential channel 7 is required for intestinal pacemaking activity.; Gastroenterology. 2005 Nov;129(5):1504-17.; Pubmed 16285951
* He Y, Yao G, Savoia C, Touyz RM.; Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II.; Circ Res. 2005 Feb 4;96(2):207-15.; Pubmed 15591230
* He Y, Yao G, Savoia C, Touyz RM.; Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II.; Circ Res. 2005 Feb 4;96(2):207-15. Epub 2004 Dec 9.; Pubmed 15591230
* Nadler MJ, Hermosura MC, Inabe K, Perraud AL, Zhu Q, Stokes AJ, Kurosaki T, Kinet JP, Penner R, Scharenberg AM, Fleig A.; LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability.; Nature 2001 May 31;411(6837):590-5; Pubmed 11385574
Gene SymbolTRPM7
Gene Full Nametransient receptor potential cation channel subfamily M member 7
Alias SymbolsALSPDC;CHAK;CHAK1;channel-kinase 1;long transient receptor potential channel 7;LTRPC ion channel family member 7;LTrpC-7;LTRPC7;transient receptor potential cation channel subfamily M member 7;transient receptor potential-phospholipase C-interacting kinase;TRP-PLIK.
NCBI Gene Id54822
Protein NameTransient receptor potential cation channel subfamily M member 7
Uniprot IDQ96QT4
Protein Accession #NP_060142.3
Molecular Weight213; 213
  1. What is the species homology for "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Dog|Human|Mouse|Porcine|Rat".

  2. How long will it take to receive "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)" provided in?

    This item is provided in "Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?

    This target may also be called "ALSPDC;CHAK;CHAK1;channel-kinase 1;long transient receptor potential channel 7;LTRPC ion channel family member 7;LTrpC-7;LTRPC7;transient receptor potential cation channel subfamily M member 7;transient receptor potential-phospholipase C-interacting kinase;TRP-PLIK." in publications.

  5. What is the shipping cost for "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "213; 213".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "TRPM7"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TRPM7"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TRPM7"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TRPM7"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TRPM7"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TRPM7"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Write Your Own Review
You're reviewing:Goat Anti-TRPM7 / LTRPC7 Antibody (OAEB01441)
Your Rating
We found other products you might like!